Efficient Synthesis Aid： 2-Chloropyrimidine-5-Boronic Acid Pinacol Ester for Boronic Acid Esters Production
Efficient Synthesis Aid: 2-Chloropyrimidine-5-Boronic Acid Pinacol Ester for Boronic Acid Esters Production
This comprehensive guide aims to provide an in-depth understanding of the product, 2-Chloropyrimidine-5-boronic acid pinacol ester, which is a highly efficient synthesis aid for the production of boronic acid esters. The article will cover various aspects of the product, including its parameters, usage scenarios, case studies, solutions, expert guidance, and FAQs to address any potential queries from users.
Product Overview
2-Chloropyrimidine-5-boronic acid pinacol ester is a versatile reagent used in the synthesis of boronic acid esters. It is a white crystalline solid with a melting point of 123-125°C. The product is highly pure, with a minimum purity of 98%. It is soluble in various organic solvents such as methanol, ethanol, and dichloromethane.
Product Parameters
| Parameter | Value |
|---|---|
| Appearance | White crystalline solid |
| Melting Point | 123-125°C |
| Purity | ≥98% |
| Solubility | Soluble in methanol, ethanol, dichloromethane |
Usage Scenarios
2-Chloropyrimidine-5-boronic acid pinacol ester is widely used in the synthesis of boronic acid esters, which are important intermediates in the pharmaceutical, agrochemical, and fine chemical industries. The following are some common usage scenarios:
- Production of boronic acid esters for pharmaceutical applications
- Synthesis of agrochemicals, such as herbicides and insecticides
- Manufacture of fine chemicals, including organic synthesis and polymerization reactions
Case Studies
Here are two case studies showcasing the use of 2-Chloropyrimidine-5-boronic acid pinacol ester in the synthesis of boronic acid esters:
Case Study 1: Synthesis of a Boronic Acid Ester for Pharmaceutical Applications
Company A, a leading pharmaceutical manufacturer, used 2-Chloropyrimidine-5-boronic acid pinacol ester to synthesize a boronic acid ester as an intermediate for a new drug. The synthesis process involved a one-pot reaction, which significantly reduced the reaction time and improved the yield. The final product met the required purity and quality standards, ensuring the successful development of the new drug.
Case Study 2: Synthesis of a Boronic Acid Ester for Agrochemical Applications
Company B, an agrochemical company, employed 2-Chloropyrimidine-5-boronic acid pinacol ester in the synthesis of a boronic acid ester as an intermediate for a new herbicide. The synthesis process was efficient, with a high yield and purity of the final product. The herbicide demonstrated excellent performance in field trials, contributing to the company's success in the agrochemical market.
Solutions
2-Chloropyrimidine-5-boronic acid pinacol ester offers several advantages in the synthesis of boronic acid esters:
- High purity and efficiency in the synthesis process
- Reduced reaction time and improved yield
- Excellent compatibility with various organic solvents
Expert Guidance
When using 2-Chloropyrimidine-5-boronic acid pinacol ester, it is essential to follow the recommended guidelines for safe handling and storage. Here are some expert tips:
- Store the product in a cool, dry place away from direct sunlight
- Handle the product with appropriate personal protective equipment, such as gloves and safety goggles
- Follow the recommended reaction conditions and procedures to ensure the desired results
FAQs
Q: What is the shelf life of 2-Chloropyrimidine-5-boronic acid pinacol ester?
A: The shelf life of the product is 2 years when stored under recommended conditions.
Q: Can 2-Chloropyrimidine-5-boronic acid pinacol ester be used in large-scale production?
A: Yes, the product is suitable for large-scale production due to its high purity and efficiency.
Conclusion
2-Chloropyrimidine-5-boronic acid pinacol ester is a valuable synthesis aid for the production of boronic acid esters. Its high purity, efficiency, and versatility make it an ideal choice for various applications in the pharmaceutical, agrochemical, and fine chemical industries. By following the recommended guidelines and expert advice, users can achieve successful synthesis outcomes.
Keywords
2-Chloropyrimidine-5-boronic acid pinacol ester, boronic acid esters, synthesis aid, pharmaceutical, agrochemical, fine chemical, intermediate, reaction, efficiency, purity
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