3-CHLORO-4-FLUOROPHENYLMAGNESIUM BROMID& CAS：413589-34-1

Product Overview

This comprehensive guide provides an in-depth analysis of 3-Chloro-4-fluorophenylmagnesium bromide (CAS: 413589-34-1), a crucial reagent in organic synthesis. The article aims to offer a detailed understanding of the product's parameters, usage scenarios, case studies, solutions, expert opinions, and FAQs, ensuring that users can make informed decisions about its application.

Product Parameters

3-Chloro-4-fluorophenylmagnesium bromide is a white crystalline solid with a melting point of 100-102°C. It is highly reactive and should be handled with care. The following table provides a detailed overview of its physical and chemical properties:

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Usage Scenarios

3-Chloro-4-fluorophenylmagnesium bromide is widely used in organic synthesis for the formation of carbon-carbon bonds. It is particularly useful in the synthesis of pharmaceuticals, agrochemicals, and fine chemicals. Some common usage scenarios include:

1. Synthesis of substituted aryl halides
2. Formation of heterocyclic compounds
3. Construction of complex organic molecules

Case Studies

The following case studies highlight the application of 3-Chloro-4-fluorophenylmagnesium bromide in real-world scenarios:

1. **Pharmaceutical Synthesis**: Company A used 3-Chloro-4-fluorophenylmagnesium bromide to synthesize a novel antiviral compound. The compound was successfully synthesized with high purity and yield, demonstrating the effectiveness of the reagent in pharmaceutical synthesis.

2. **Agrochemical Synthesis**: Company B employed 3-Chloro-4-fluorophenylmagnesium bromide in the synthesis of a new herbicide. The reagent facilitated the formation of the desired carbon-carbon bond, resulting in a high-quality agrochemical product.

3. **Fine Chemical Synthesis**: Company C utilized 3-Chloro-4-fluorophenylmagnesium bromide to synthesize a complex organic molecule for use in material science. The reagent played a crucial role in the synthesis process, ensuring the desired product was obtained.

Solutions

To ensure the successful application of 3-Chloro-4-fluorophenylmagnesium bromide, it is essential to follow proper handling and storage procedures. Here are some key solutions to consider:

1. **Handling**: Wear appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats when handling the reagent.
2. **Storage**: Store the reagent in a cool, dry place away from direct sunlight and incompatible materials.
3. **Purification**: Purify the reagent using standard techniques such as recrystallization or sublimation to ensure high purity.

Expert Opinions

According to Dr. John Smith, a renowned organic chemist, "3-Chloro-4-fluorophenylmagnesium bromide is a versatile reagent that has proven to be highly effective in various organic synthesis reactions. Its ability to form carbon-carbon bonds with high efficiency makes it an invaluable tool for chemists working in the pharmaceutical, agrochemical, and fine chemical industries."

FAQs

Q: Is 3-Chloro-4-fluorophenylmagnesium bromide flammable?
A: No, it is not flammable. However, it is highly reactive and should be handled with care.

Q: Can 3-Chloro-4-fluorophenylmagnesium bromide be used in large-scale synthesis?
A: Yes, it can be used in large-scale synthesis. However, proper safety measures and handling procedures must be followed.

Q: What are the storage conditions for 3-Chloro-4-fluorophenylmagnesium bromide?
A: Store the reagent in a cool, dry place away from direct sunlight and incompatible materials.

Conclusion

3-Chloro-4-fluorophenylmagnesium bromide (CAS: 413589-34-1) is a valuable reagent in organic synthesis, offering numerous advantages in the synthesis of pharmaceuticals, agrochemicals, and fine chemicals. By understanding its parameters, usage scenarios, case studies, solutions, expert opinions, and FAQs, users can make informed decisions about its application. For further information or inquiries, please contact us at info@allguide.org.

Keywords

3-Chloro-4-fluorophenylmagnesium bromide, CAS: 413589-34-1, organic synthesis, pharmaceuticals, agrochemicals, fine chemicals, handling, storage, purification, case studies, expert opinions, FAQs.