Effective Nausea Relief: Granisetron Hydrochloride CAS 107007-99-8 for Clinical Use

Effective Nausea Relief: Granisetron Hydrochloride CAS 107007-99-8 for Clinical Use

Granisetron Hydrochloride, with the CAS number 107007-99-8, is a potent antiemetic drug widely used in clinical settings for the relief of nausea and vomiting. This comprehensive guide aims to provide an in-depth understanding of Granisetron Hydrochloride, its parameters, usage scenarios, case studies, solutions, and expert guidance, ensuring effective nausea relief for patients.

Product Overview

Granisetron Hydrochloride is a selective serotonin receptor antagonist, primarily used to prevent nausea and vomiting associated with chemotherapy, radiotherapy, and postoperative settings. It is available in various formulations, including oral tablets, intravenous solutions, and subcutaneous injections.

Product Parameters

Parameter Value
Chemical Formula C17H19Cl2N3O3
Molecular Weight 367.27 g/mol
Appearance White to off-white crystalline powder
Solubility Soluble in water, sparingly soluble in ethanol

Usage Scenarios

Granisetron Hydrochloride is primarily used in the following scenarios:

  • Chemotherapy-induced nausea and vomiting (CINV)
  • Radiotherapy-induced nausea and vomiting (RINV)
  • Postoperative nausea and vomiting (PONV)
  • Other causes of nausea and vomiting, such as motion sickness and vertigo

Case Studies

Here are two real-life case studies showcasing the effectiveness of Granisetron Hydrochloride in clinical settings:

Case Study 1: Chemotherapy-induced Nausea and Vomiting

A 65-year-old female patient with breast cancer was undergoing chemotherapy. She experienced severe nausea and vomiting, which significantly impacted her quality of life. After being prescribed Granisetron Hydrochloride, her symptoms improved significantly, allowing her to continue her treatment without interruption.

Case Study 2: Radiotherapy-induced Nausea and Vomiting

A 50-year-old male patient with lung cancer was undergoing radiotherapy. He experienced persistent nausea and vomiting, which made it difficult for him to complete his treatment. After being administered Granisetron Hydrochloride, his symptoms were effectively managed, enabling him to complete his radiotherapy regimen.

Solutions

Granisetron Hydrochloride offers several solutions for nausea and vomiting management:

  • Prevention of nausea and vomiting during chemotherapy, radiotherapy, and postoperative settings
  • Management of chronic nausea and vomiting associated with various conditions
  • Reduction of the need for antiemetic rescue medications

Expert Guidance

When using Granisetron Hydrochloride, it is essential to follow expert guidance:

  • Administer the appropriate dosage based on the patient's age, weight, and condition
  • Monitor the patient for any adverse reactions or side effects
  • Adjust the dosage as necessary to achieve optimal relief

Conclusion

Granisetron Hydrochloride, with the CAS number 107007-99-8, is a highly effective antiemetic drug for the relief of nausea and vomiting in clinical settings. Its various formulations, usage scenarios, and case studies demonstrate its efficacy in managing nausea and vomiting associated with chemotherapy, radiotherapy, and postoperative settings. By following expert guidance and adhering to the recommended dosage, healthcare professionals can ensure effective nausea relief for their patients.

Keywords

Granisetron Hydrochloride, CAS 107007-99-8, nausea relief, antiemetic, chemotherapy, radiotherapy, postoperative, case studies, expert guidance

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FQA

Q: What is Granisetron Hydrochloride used for?
A: Granisetron Hydrochloride is primarily used for the prevention and treatment of nausea and vomiting associated with chemotherapy, radiotherapy, and postoperative settings.

Q: How does Granisetron Hydrochloride work?
A: Granisetron Hydrochloride is a selective serotonin receptor antagonist that blocks the serotonin receptors in the brain, thereby reducing the sensation of nausea and vomiting.

Q: What are the common side effects of Granisetron Hydrochloride?
A: Common side effects of Granisetron Hydrochloride include headache, constipation, and dizziness. In rare cases, it may cause serious side effects such as serotonin syndrome.

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