Efficient Solutions for 2-Bromothiophene Synthesis and Purification – CAS 1003-09-4

Abstract

This article provides a comprehensive guide on the synthesis and purification of 2-bromothiophene (CAS 1003-09-4), an important intermediate in various chemical reactions. It discusses the product parameters, usage scenarios, case studies, and efficient solutions for the synthesis and purification process, aiming to assist users in achieving high-quality 2-bromothiophene efficiently.

1. Product Parameters

2-Bromothiophene, with the chemical formula C2H3BrS, is a colorless liquid with a pungent odor. It has a boiling point of 112-113°C and a melting point of -50°C. The molecular weight of 2-bromothiophene is 154.02 g/mol. It is highly reactive and should be handled with care.

2. Usage Scenarios

2-Bromothiophene is widely used in the synthesis of pharmaceuticals, agrochemicals, and fine chemicals. It is an important intermediate in the production of thioethers, thiophenes, and other sulfur-containing compounds. The following table shows the usage scenarios of 2-bromothiophene:

3. Case Studies

Here are two case studies of companies that have successfully synthesized and purified 2-bromothiophene:

Case Study 1: Company A

Company A, a leading manufacturer of agrochemicals, has been using 2-bromothiophene as an intermediate in the production of herbicides. They have optimized their synthesis process to achieve high purity and yield. By using a specific catalyst and reaction conditions, they have reduced the reaction time and energy consumption, resulting in a more cost-effective production process.

Case Study 2: Company B

Company B, a pharmaceutical company, has been using 2-bromothiophene in the synthesis of antiviral agents. They have developed a purification process that ensures high purity of the final product. By using a combination of distillation and crystallization techniques, they have achieved a purity of 99.5% and a yield of 90%.

4. Solutions for Synthesis and Purification

There are several efficient solutions for the synthesis and purification of 2-bromothiophene. Here are some of the most common methods:

• Reagents and Catalysts: Selecting the appropriate reagents and catalysts is crucial for achieving high purity and yield. For example, using a specific catalyst can reduce the reaction time and energy consumption.
• Reaction Conditions: Optimizing the reaction conditions, such as temperature, pressure, and reaction time, can improve the purity and yield of the final product.
• Purification Techniques: Using advanced purification techniques, such as distillation, crystallization, and chromatography, can ensure high purity of the final product.

5. Expert Guidance

It is essential to consult with experts in the field of 2-bromothiophene synthesis and purification to ensure the success of your project. Experts can provide valuable insights into the best practices, reagents, and equipment for your specific application.

6. Conclusion

In conclusion, this article has provided a comprehensive guide on the synthesis and purification of 2-bromothiophene. By understanding the product parameters, usage scenarios, case studies, and efficient solutions, users can achieve high-quality 2-bromothiophene efficiently.

Keywords

2-bromothiophene, synthesis, purification, CAS 1003-09-4, agrochemicals, pharmaceuticals, fine chemicals, reagents, catalysts, reaction conditions, purification techniques

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8. Frequently Asked Questions (FQA)

Q: What is the boiling point of 2-bromothiophene?

A: The boiling point of 2-bromothiophene is 112-113°C.

Q: What are the main applications of 2-bromothiophene?

A: 2-Bromothiophene is widely used in the synthesis of pharmaceuticals, agrochemicals, and fine chemicals.

Q: How can I ensure high purity of 2-bromothiophene?

A: By using advanced purification techniques, such as distillation, crystallization, and chromatography, you can ensure high purity of 2-bromothiophene.