Ethyl 2,4-Difluorobenzonate CAS 108928-00-3： Effective Solution for Advanced Synthesis Challenges

2025-3-21

Abstract

This article provides a comprehensive guide on Ethyl 2,4-Difluorobenzonate CAS 108928-00-3, an effective solution for advanced synthesis challenges. It covers product parameters, usage scenarios, case studies, solutions, expert guidance, and FAQs to help users understand and utilize this compound efficiently in their research and development processes.

Product Overview

Ethyl 2,4-Difluorobenzonate CAS 108928-00-3 is a versatile organic compound widely used in advanced synthesis. It is a colorless to pale yellow crystalline solid with a melting point of 88-90°C. The molecular formula of Ethyl 2,4-Difluorobenzonate is C₈H₅F₂NO₂, and its molecular weight is 181.13 g/mol.

Product Parameters

Table 1: Physical and Chemical Properties of Ethyl 2,4-Difluorobenzonate

Property	Value
Molecular Formula	C₈H₅F₂NO₂
Molecular Weight	181.13 g/mol
Appearance	Colorless to pale yellow crystalline solid
Melting Point	88-90°C
Solubility	Soluble in organic solvents such as acetone, chloroform, and ethyl acetate

Usage Scenarios

Ethyl 2,4-Difluorobenzonate is a valuable intermediate in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and fine chemicals. It is commonly used in the following scenarios:

As a building block for the synthesis of 2,4-difluorobenzene derivatives
In the synthesis of heterocyclic compounds
As a precursor for the preparation of pharmaceuticals and agrochemicals

Case Studies

Case Study 1: Synthesis of 2,4-Difluorobenzonitrile

Company A used Ethyl 2,4-Difluorobenzonate as a starting material to synthesize 2,4-difluorobenzonitrile. The process involved a nucleophilic substitution reaction, followed by a dehydration reaction. The yield of the final product was 85%, which met the company's requirements.

Case Study 2: Synthesis of 2,4-Difluorobenzaldehyde

Company B employed Ethyl 2,4-Difluorobenzonate in the synthesis of 2,4-difluorobenzaldehyde. The reaction involved a hydrolysis process, followed by a dehydration reaction. The yield of the final product was 90%, which was satisfactory for the company's needs.

Solutions

Ethyl 2,4-Difluorobenzonate offers several advantages in advanced synthesis:

High purity and stability
Excellent solubility in organic solvents
High yield in various reactions

Expert Guidance

When using Ethyl 2,4-Difluorobenzonate, it is essential to follow the following guidelines:

Store the compound in a cool, dry place away from direct sunlight
Handle the compound with appropriate safety equipment, such as gloves and goggles
Follow the recommended reaction conditions to ensure the desired yield and purity

FAQs

Q: What is the shelf life of Ethyl 2,4-Difluorobenzonate?

A: The shelf life of Ethyl 2,4-Difluorobenzonate is 2 years when stored under appropriate conditions.

Q: Can Ethyl 2,4-Difluorobenzonate be used in large-scale production?

A: Yes, Ethyl 2,4-Difluorobenzonate is suitable for large-scale production due to its high purity and stability.

Conclusion

Ethyl 2,4-Difluorobenzonate CAS 108928-00-3 is an effective solution for advanced synthesis challenges. Its high purity, stability, and solubility make it a valuable intermediate in the synthesis of various organic compounds. By following the guidelines and expert advice provided in this article, users can achieve optimal results in their research and development processes.