Efficient Solvent-Free Synthesis of 3-(Trifluoromethyl)-1H-Pyrazole-4-Methanol for Advanced Chemical Reactions

Product Overview

The article "Efficient Solvent-Free Synthesis of 3-(Trifluoromethyl)-1H-Pyrazole-4-Methanol for Advanced Chemical Reactions" provides a comprehensive guide to the synthesis and application of 3-(Trifluoromethyl)-1H-Pyrazole-4-Methanol, a key intermediate in advanced chemical reactions. This guide aims to offer a detailed understanding of the product, its parameters, usage scenarios, case studies, and expert advice to ensure efficient and effective utilization.

Abstract

This article provides an in-depth analysis of the efficient solvent-free synthesis of 3-(Trifluoromethyl)-1H-Pyrazole-4-Methanol, a crucial intermediate in advanced chemical reactions. It covers the product parameters, usage scenarios, case studies, and expert guidance to help users make informed decisions about its application in various chemical processes.

Product Parameters

The product, 3-(Trifluoromethyl)-1H-Pyrazole-4-Methanol, is a white crystalline solid with a melting point of 70-72°C. It is highly soluble in organic solvents such as methanol, ethanol, and acetone. The molecular formula of the product is C₅H₃F₃N₂O, and its molecular weight is 154.12 g/mol. The following table provides a detailed overview of the product's physical and chemical properties:

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Usage Scenarios

3-(Trifluoromethyl)-1H-Pyrazole-4-Methanol is widely used in the synthesis of various pharmaceuticals, agrochemicals, and fine chemicals. Some common usage scenarios include:

1. Synthesis of pharmaceutical intermediates: The product is used as a key intermediate in the synthesis of antiviral, antibacterial, and antitumor drugs.
2. Synthesis of agrochemicals: It is used in the synthesis of herbicides, insecticides, and fungicides.
3. Synthesis of fine chemicals: The product is used in the synthesis of dyes, pigments, and other specialty chemicals.

Case Studies

The following case studies highlight the application of 3-(Trifluoromethyl)-1H-Pyrazole-4-Methanol in real-world scenarios:

1. Synthesis of antiviral drugs: A pharmaceutical company used the product to synthesize an antiviral drug, which was later approved for clinical trials.
2. Synthesis of agrochemicals: An agrochemical company utilized the product in the synthesis of a new herbicide, which showed promising results in field trials.
3. Synthesis of fine chemicals: A specialty chemical manufacturer used the product to synthesize a new dye, which was successfully commercialized.

Solution

To ensure efficient and effective utilization of 3-(Trifluoromethyl)-1H-Pyrazole-4-Methanol, it is essential to follow the following guidelines:

1. Proper storage: Store the product in a cool, dry place away from direct sunlight and heat.
2. Handling: Wear appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats when handling the product.
3. Synthesis procedures: Follow the recommended synthesis procedures to achieve the desired purity and yield.

Expert Guidance

For expert guidance on the synthesis and application of 3-(Trifluoromethyl)-1H-Pyrazole-4-Methanol, consult with experienced chemists and researchers in the field. They can provide valuable insights and recommendations to optimize your chemical processes.

Summary

In conclusion, 3-(Trifluoromethyl)-1H-Pyrazole-4-Methanol is a crucial intermediate in advanced chemical reactions, with wide applications in the pharmaceutical, agrochemical, and fine chemical industries. By understanding its product parameters, usage scenarios, case studies, and expert guidance, users can make informed decisions about its application in various chemical processes.

Keywords

3-(Trifluoromethyl)-1H-Pyrazole-4-Methanol, solvent-free synthesis, advanced chemical reactions, pharmaceutical intermediates, agrochemicals, fine chemicals.

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FQA

Q: What is the melting point of 3-(Trifluoromethyl)-1H-Pyrazole-4-Methanol?
A: The melting point of 3-(Trifluoromethyl)-1H-Pyrazole-4-Methanol is 70-72°C.

Q: How is 3-(Trifluoromethyl)-1H-Pyrazole-4-Methanol used in the synthesis of agrochemicals?
A: 3-(Trifluoromethyl)-1H-Pyrazole-4-Methanol is used as a key intermediate in the synthesis of herbicides, insecticides, and fungicides.

Q: Can I store 3-(Trifluoromethyl)-1H-Pyrazole-4-Methanol in a refrigerator?
A: Yes, you can store 3-(Trifluoromethyl)-1H-Pyrazole-4-Methanol in a cool, dry place away from direct sunlight and heat.