Efficient Synthesis of 5-Bromo-2-Methyl-4-Pyrimidinecarboxylic Acid： Your Ultimate Solution for Drug Development

2025-3-21

Efficient Synthesis of 5-Bromo-2-Methyl-4-Pyrimidinecarboxylic Acid: Your Ultimate Solution for Drug Development

Efficient Synthesis of 5-Bromo-2-Methyl-4-Pyrimidinecarboxylic Acid is a cutting-edge product designed to streamline the synthesis process for drug development. This guide will provide an in-depth analysis of the product, including its parameters, usage scenarios, case studies, solutions, expert guidance, and frequently asked questions. By the end of this article, you will have a comprehensive understanding of how this product can be your ultimate solution for drug development.

Product Overview

5-Bromo-2-Methyl-4-Pyrimidinecarboxylic Acid is a key intermediate in the synthesis of various pharmaceuticals. It is widely used in the development of antiviral, antibacterial, and antitumor drugs. The efficient synthesis of this compound is crucial for the pharmaceutical industry, as it reduces production costs and shortens the time-to-market for new drugs.

Product Parameters

The product is available in high purity (≥98%) and is suitable for various synthetic methods. The molecular formula of 5-Bromo-2-Methyl-4-Pyrimidinecarboxylic Acid is C₆H₄N₂BrO₂, and its molecular weight is 254.97 g/mol. The product is a white to off-white crystalline solid, and it is stable under normal storage conditions.

Usage Scenarios

5-Bromo-2-Methyl-4-Pyrimidinecarboxylic Acid is used in various synthetic pathways for the preparation of pharmaceuticals. Some common usage scenarios include:

Antiviral drugs: The compound can be used as a starting material for the synthesis of antiviral agents, such as acyclovir and valacyclovir.
Antibacterial drugs: The compound can be used to synthesize antibacterial agents, such as ciprofloxacin and norfloxacin.
Antitumor drugs: The compound can be used as a building block for the synthesis of antitumor agents, such as 5-fluorouracil and capecitabine.

Case Studies

Here are two case studies demonstrating the use of 5-Bromo-2-Methyl-4-Pyrimidinecarboxylic Acid in drug development:

Case Study 1: Synthesis of Acyclovir

Acyclovir is an antiviral drug used to treat herpes simplex virus (HSV) infections. The synthesis of acyclovir involves the conversion of 5-Bromo-2-Methyl-4-Pyrimidinecarboxylic Acid to 5-bromouracil, followed by the addition of guanidine and hydrolysis. This process is facilitated by the efficient synthesis of 5-Bromo-2-Methyl-4-Pyrimidinecarboxylic Acid, which ensures high yields and purity of the final product.

Case Study 2: Synthesis of Ciprofloxacin

Ciprofloxacin is an antibacterial drug used to treat various bacterial infections. The synthesis of ciprofloxacin involves the conversion of 5-Bromo-2-Methyl-4-Pyrimidinecarboxylic Acid to 5-bromopyrimidine, followed by the addition of various functional groups. The efficient synthesis of 5-Bromo-2-Methyl-4-Pyrimidinecarboxylic Acid is essential for the successful synthesis of ciprofloxacin, as it ensures high yields and purity of the intermediate.

Solutions

Efficient Synthesis of 5-Bromo-2-Methyl-4-Pyrimidinecarboxylic Acid offers several solutions for drug development:

High purity: The product is available in high purity, ensuring the quality of the final drug product.
Efficient synthesis: The product is designed for efficient synthesis, reducing production costs and time-to-market.
Customization: The product can be customized to meet specific requirements for drug development.

Expert Guidance

Our team of experts is available to provide guidance on the use of 5-Bromo-2-Methyl-4-Pyrimidinecarboxylic Acid in drug development. We can assist with:

Selection of the appropriate synthetic method
Optimization of reaction conditions
Quality control and analysis

Frequently Asked Questions (FQA)

Q: What is the purity of 5-Bromo-2-Methyl-4-Pyrimidinecarboxylic Acid?

A: The product is available in high purity (≥98%) and meets the requirements for pharmaceutical applications.

Q: How does 5-Bromo-2-Methyl-4-Pyrimidinecarboxylic Acid compare to other intermediates in terms of efficiency?

A: 5-Bromo-2-Methyl-4-Pyrimidinecarboxylic Acid offers an efficient synthesis route, resulting in high yields and purity of the final product.

Conclusion

Efficient Synthesis of 5-Bromo-2-Methyl-4-Pyrimidinecarboxylic Acid is a valuable tool for drug development. Its high purity, efficient synthesis, and customization options make it an ideal choice for pharmaceutical manufacturers. By using this product, you can streamline the drug development process, reduce production costs, and accelerate the time-to-market for new drugs.

Keywords

5-Bromo-2-Methyl-4-Pyrimidinecarboxylic Acid, drug development, pharmaceutical intermediates, antiviral drugs, antibacterial drugs, antitumor drugs, synthesis, efficiency, purity