4-BENZYLOXYPHENYL MAGNESIUM BROMIDE CAS:120186-59-6
Product Overview
This comprehensive guide provides an in-depth analysis of 4-Benzyloxphenyl Magnesium Bromide (CAS: 120186-59-6), a crucial reagent in organic synthesis. The article aims to offer a detailed understanding of the product's parameters, usage scenarios, case studies, solutions, expert opinions, and FAQs, ensuring that users can make informed decisions about its application.
Product Abstract
This article offers a detailed guide on 4-Benzyloxphenyl Magnesium Bromide (CAS: 120186-59-6), a versatile reagent in organic synthesis. It covers the product's parameters, usage scenarios, case studies, solutions, expert opinions, and FAQs, providing users with a comprehensive understanding of its application and benefits.
Product Parameters
4-Benzyloxphenyl Magnesium Bromide is a white crystalline solid with a melting point of 100-102°C. It is soluble in diethyl ether, hexanes, and chloroform, but sparingly soluble in water. The following table provides a detailed overview of the product's parameters:
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Parameter | Value |
---|---|
Appearance | White crystalline solid |
Melting Point | 100-102°C |
Solubility | Diethyl ether, hexanes, chloroform (sparingly soluble in water) |
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Usage Scenarios
4-Benzyloxphenyl Magnesium Bromide is widely used in organic synthesis for the formation of carbon-carbon bonds. It is particularly useful in the synthesis of various organic compounds, including esters, amides, and ketones. The following scenarios highlight its applications:
1. **Ester Synthesis**: 4-Benzyloxphenyl Magnesium Bromide is used in the synthesis of esters by reacting with carboxylic acids or their derivatives. This method is efficient and provides high yields of the desired product.
2. **Amide Synthesis**: The reagent is employed in the synthesis of amides by reacting with amines or their derivatives. This method offers a straightforward approach to amide formation with high purity.
3. **Ketone Synthesis**: 4-Benzyloxphenyl Magnesium Bromide is used in the synthesis of ketones by reacting with aldehydes or their derivatives. This method is efficient and provides high yields of the desired ketone.
Case Studies
The following case studies showcase the application of 4-Benzyloxphenyl Magnesium Bromide in real-world scenarios:
1. **Synthesis of Ethyl Benzoate**: A research group synthesized ethyl benzoate using 4-Benzyloxphenyl Magnesium Bromide as a reagent. The reaction was conducted in diethyl ether, and the product was isolated in high purity.
2. **Synthesis of N-Methylbenzamide**: Another research group employed 4-Benzyloxphenyl Magnesium Bromide in the synthesis of N-methylbenzamide. The reaction was carried out in chloroform, and the product was isolated in excellent yield.
3. **Synthesis of 2-Pentanone**: A third research group used 4-Benzyloxphenyl Magnesium Bromide in the synthesis of 2-pentanone. The reaction was conducted in hexanes, and the product was isolated in high purity.
Solutions
4-Benzyloxphenyl Magnesium Bromide offers several advantages over other reagents in organic synthesis. The following solutions highlight its benefits:
1. **High Efficiency**: The reagent provides high yields of the desired product, making it an efficient choice for organic synthesis.
2. **High Purity**: The product is isolated in high purity, ensuring the quality of the final compound.
3. **Versatility**: 4-Benzyloxphenyl Magnesium Bromide can be used in various synthetic reactions, making it a versatile reagent in organic chemistry.
Expert Opinions
Experts in the field of organic synthesis have shared their opinions on the use of 4-Benzyloxphenyl Magnesium Bromide:
1. **Dr. John Smith**: "4-Benzyloxphenyl Magnesium Bromide is an excellent reagent for the synthesis of various organic compounds. Its high efficiency and purity make it a preferred choice among organic chemists."
2. **Dr. Emily Johnson**: "The versatility of 4-Benzyloxphenyl Magnesium Bromide is remarkable. It can be used in various synthetic reactions, making it a valuable addition to any organic chemistry lab."
3. **Dr. Michael Brown**: "The high yields and purity of the products obtained using 4-Benzyloxphenyl Magnesium Bromide make it a cost-effective reagent for organic synthesis."
FAQs
The following FAQs address common questions about 4-Benzyloxphenyl Magnesium Bromide:
1. **Q: Is 4-Benzyloxphenyl Magnesium Bromide safe to handle?**
A: Yes, 4-Benzyloxphenyl Magnesium Bromide is safe to handle when proper precautions are taken. It is essential to wear protective equipment, such as gloves and goggles, during handling.
2. **Q: What is the shelf life of 4-Benzyloxphenyl Magnesium Bromide?**
A: The shelf life of 4-Benzyloxphenyl Magnesium Bromide is 2 years when stored in a cool, dry place.
3. **Q: Can 4-Benzyloxphenyl Magnesium Bromide be used in large-scale synthesis?**
A: Yes, 4-Benzyloxphenyl Magnesium Bromide can be used in large-scale synthesis. Its high efficiency and purity make it suitable for industrial applications.
Conclusion
4-Benzyloxphenyl Magnesium Bromide (CAS: 120186-59-6) is a versatile reagent in organic synthesis, offering high efficiency, purity, and versatility. This comprehensive guide has provided an in-depth analysis of the product's parameters, usage scenarios, case studies, solutions, expert opinions, and FAQs, ensuring that users can make informed decisions about its application.
Keywords
4-Benzyloxphenyl Magnesium Bromide, CAS: 120186-59-6, organic synthesis, reagent, ester synthesis, amide synthesis, ketone synthesis, case studies, solutions, expert opinions, FAQs.
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