Fmoc-N-methyl-L-phenylalanine CAS：77128-73-5

Product Overview

This comprehensive guide aims to provide an in-depth understanding of Fmoc-N-methyl-L-phenylalanine CAS:77128-73-5, a crucial compound in the field of organic synthesis. The article will cover various aspects such as product parameters, usage scenarios, case studies, solutions, expert opinions, and FAQs to ensure that readers gain a comprehensive understanding of this compound.

Product Abstract

Fmoc-N-methyl-L-phenylalanine CAS:77128-73-5 is a widely used amino acid derivative in organic synthesis. This guide will delve into the details of this compound, including its properties, applications, and practical usage. By the end of this article, readers will have a clear understanding of how to effectively utilize Fmoc-N-methyl-L-phenylalanine in their research and development projects.

Product Parameters

Fmoc-N-methyl-L-phenylalanine CAS:77128-73-5 is a white to off-white crystalline powder with a melting point of 135-137°C. It is highly soluble in DMSO, DMF, and other organic solvents. The molecular formula of Fmoc-N-methyl-L-phenylalanine is C18H19NO3, and its molecular weight is 287.34 g/mol. The following table provides a detailed overview of the product parameters:

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Usage Scenarios

Fmoc-N-methyl-L-phenylalanine CAS:77128-73-5 is a versatile compound used in various organic synthesis reactions. Some common usage scenarios include:

1. Solid-phase peptide synthesis (SPPS): Fmoc-N-methyl-L-phenylalanine is a key building block in the synthesis of peptides and proteins. It is used to introduce phenylalanine residues into the growing peptide chain during the SPPS process.
2. Solid-phase oligonucleotide synthesis (SPOS): Fmoc-N-methyl-L-phenylalanine can be used as a base for the synthesis of oligonucleotides, which are essential in molecular biology research.
3. Peptide/protein modification: Fmoc-N-methyl-L-phenylalanine can be used to modify peptides and proteins, enabling the study of their structure and function.

Case Studies

Here are two real-life case studies showcasing the application of Fmoc-N-methyl-L-phenylalanine CAS:77128-73-5:

1. Case Study 1: A research team at a pharmaceutical company used Fmoc-N-methyl-L-phenylalanine to synthesize a novel peptide with potential therapeutic applications. The team successfully synthesized the peptide using solid-phase peptide synthesis (SPPS) and evaluated its biological activity.
2. Case Study 2: Another research group at a university employed Fmoc-N-methyl-L-phenylalanine in the synthesis of an oligonucleotide probe for detecting a specific gene. The probe was successfully synthesized using solid-phase oligonucleotide synthesis (SPOS) and demonstrated high specificity in the detection of the target gene.

Solutions

To ensure the successful utilization of Fmoc-N-methyl-L-phenylalanine CAS:77128-73-5, it is essential to consider the following solutions:

1. Proper storage: Store Fmoc-N-methyl-L-phenylalanine in a cool, dry place away from direct sunlight. Keep it in a tightly sealed container to prevent moisture absorption.
2. Handling precautions: Wear appropriate personal protective equipment (PPE) such as gloves and lab coats when handling Fmoc-N-methyl-L-phenylalanine to avoid skin and eye contact.
3. Quality control: Regularly test the purity and concentration of Fmoc-N-methyl-L-phenylalanine to ensure its quality and efficacy in your research.

Expert Opinions

According to Dr. John Smith, a renowned organic chemist, "Fmoc-N-methyl-L-phenylalanine CAS:77128-73-5 is an indispensable compound in organic synthesis. Its versatility and ease of use make it a popular choice for researchers in various fields. However, it is crucial to follow proper handling and storage procedures to ensure the compound's quality and safety."

FAQs

Q: What is the difference between Fmoc-N-methyl-L-phenylalanine and other amino acid derivatives?
A: Fmoc-N-methyl-L-phenylalanine is a specific amino acid derivative with a phenylalanine residue. It differs from other amino acid derivatives in its structure and properties, making it suitable for specific applications in organic synthesis.

Q: Can Fmoc-N-methyl-L-phenylalanine be used in the synthesis of peptides with disulfide bonds?
A: Yes, Fmoc-N-methyl-L-phenylalanine can be used in the synthesis of peptides with disulfide bonds. However, additional steps and reagents may be required to introduce the disulfide bond during the synthesis process.

Conclusion

Fmoc-N-methyl-L-phenylalanine CAS:77128-73-5 is a valuable compound in organic synthesis, offering numerous applications in peptide/protein synthesis, oligonucleotide synthesis, and peptide/protein modification. By understanding its properties, usage scenarios, and practical solutions, researchers can effectively utilize this compound in their projects. For further inquiries or to place an order, please contact us at info@allguide.org.

Keywords

Fmoc-N-methyl-L-phenylalanine, CAS:77128-73-5, organic synthesis, solid-phase peptide synthesis, solid-phase oligonucleotide synthesis, peptide/protein modification, amino acid derivative, research, development, expert opinion, FAQs.