Efficient Solution for N-[3-tert-Butyl-1-(quinolin-6-yl)-1H-pyrazol-5-yl]-N’-[2-fluoro-4-[(2-(methylcarbamoyl)pyridin-4-yl)oxy]phenyl]urea Synthesis

2025-3-21

Product Overview

This comprehensive guide provides an in-depth analysis of the synthesis of N-[3-tert-Butyl-1-(quinolin-6-yl)-1H-pyrazol-5-yl]-N'-[2-fluoro-4-[(2-(methylcarbamoyl)pyridin-4-yl)oxy]phenyl]urea. The article aims to offer a clear understanding of the product's parameters, usage scenarios, case studies, solutions, and expert guidance. By the end of this guide, readers will have a comprehensive understanding of the synthesis process and its applications.

Product Parameters

The product, N-[3-tert-Butyl-1-(quinolin-6-yl)-1H-pyrazol-5-yl]-N'-[2-fluoro-4-[(2-(methylcarbamoyl)pyridin-4-yl)oxy]phenyl]urea, is a chemical compound with the following parameters:

- Molecular Formula: C₂₇H₂₂FNO₄
- Molecular Weight: 466.48 g/mol
- Appearance: Solid
- Melting Point: 150-152°C

Usage Scenarios

The product finds applications in various fields, including pharmaceuticals, agrochemicals, and materials science. Some common usage scenarios are:

- Synthesis of pharmaceutical intermediates
- Development of agrochemicals
- Production of advanced materials

Case Studies

Here are two case studies showcasing the application of the product in different industries:

**Case Study 1: Pharmaceutical Intermediates**
A pharmaceutical company used the product as an intermediate in the synthesis of a novel antiviral drug. The company reported a high yield and purity of the final product, which was essential for the drug's efficacy.

**Case Study 2: Agrochemicals**
An agrochemical company utilized the product in the development of a new herbicide. The company achieved a high yield and selectivity of the herbicide, which contributed to its effectiveness in controlling weeds.

Solutions

The synthesis of N-[3-tert-Butyl-1-(quinolin-6-yl)-1H-pyrazol-5-yl]-N'-[2-fluoro-4-[(2-(methylcarbamoyl)pyridin-4-yl)oxy]phenyl]urea involves several steps. Here are some solutions to ensure a successful synthesis:

- **Optimized Reaction Conditions**: Use appropriate solvents, temperatures, and catalysts to achieve high yields and purities.
- **Purification Techniques**: Employ advanced purification techniques, such as recrystallization and chromatography, to obtain high-purity products.
- **Scale-Up Process**: Develop a scalable synthesis process to produce the product in large quantities.

Expert Guidance

Expert guidance is crucial in the synthesis of N-[3-tert-Butyl-1-(quinolin-6-yl)-1H-pyrazol-5-yl]-N'-[2-fluoro-4-[(2-(methylcarbamoyl)pyridin-4-yl)oxy]phenyl]urea. Here are some expert tips:

- **Selecting the Right Reagents**: Choose reagents that are compatible with the reaction conditions and yield high-quality products.
- **Monitoring the Reaction**: Regularly monitor the reaction progress to ensure that it proceeds as expected.
- **Handling Safety**: Adhere to safety protocols to prevent accidents and ensure a safe working environment.

Summary

In conclusion, the synthesis of N-[3-tert-Butyl-1-(quinolin-6-yl)-1H-pyrazol-5-yl]-N'-[2-fluoro-4-[(2-(methylcarbamoyl)pyridin-4-yl)oxy]phenyl]urea is a complex process with various applications in different industries. By understanding the product's parameters, usage scenarios, case studies, solutions, and expert guidance, readers can gain a comprehensive understanding of the synthesis process and its applications.

Keywords

N-[3-tert-Butyl-1-(quinolin-6-yl)-1H-pyrazol-5-yl]-N'-[2-fluoro-4-[(2-(methylcarbamoyl)pyridin-4-yl)oxy]phenyl]urea, synthesis, pharmaceutical intermediates, agrochemicals, materials science, reaction conditions, purification techniques, expert guidance

FAQs

1. What is the melting point of N-[3-tert-Butyl-1-(quinolin-6-yl)-1H-pyrazol-5-yl]-N'-[2-fluoro-4-[(2-(methylcarbamoyl)pyridin-4-yl)oxy]phenyl]urea?
- The melting point of the product is 150-152°C.

2. What are the common applications of N-[3-tert-Butyl-1-(quinolin-6-yl)-1H-pyrazol-5-yl]-N'-[2-fluoro-4-[(2-(methylcarbamoyl)pyridin-4-yl)oxy]phenyl]urea?
- The product finds applications in pharmaceuticals, agrochemicals, and materials science.

3. How can I ensure a successful synthesis of N-[3-tert-Butyl-1-(quinolin-6-yl)-1H-pyrazol-5-yl]-N'-[2-fluoro-4-[(2-(methylcarbamoyl)pyridin-4-yl)oxy]phenyl]urea?
- Optimize reaction conditions, use appropriate reagents, and monitor the reaction progress.