Unlock Advanced Synthesis Solutions with 1,4-Dimethylpyrazole CAS 1072-68-0 for Efficient Chemical Reactions

2025-3-21

Unlock Advanced Synthesis Solutions with 1,4-Dimethylpyrazole CAS 1072-68-0 for Efficient Chemical Reactions

1,4-Dimethylpyrazole CAS 1072-68-0 is a versatile organic compound that has gained significant attention in the field of chemical synthesis. This guide aims to provide a comprehensive overview of the product, including its parameters, usage scenarios, case studies, and solutions for efficient chemical reactions. By understanding the benefits and applications of 1,4-Dimethylpyrazole, researchers and chemists can unlock advanced synthesis solutions for their chemical reactions.

Product Overview

1,4-Dimethylpyrazole, with the chemical formula C₅H₇N, is a white crystalline solid. It has a melting point of 57-59°C and a boiling point of 194-196°C. The compound is soluble in organic solvents such as chloroform, acetone, and ethanol. It is also stable under normal storage conditions and has a shelf life of 2 years.

Product Parameters

Parameter	Value
Chemical Formula	C₅H₇N
Molecular Weight	83.12 g/mol
Melting Point	57-59°C
Boiling Point	194-196°C
Shelf Life	2 years

Usage Scenarios

1,4-Dimethylpyrazole is widely used in various chemical reactions, including:

1. Synthesis of heterocyclic compounds: 1,4-Dimethylpyrazole can be used as a building block for the synthesis of heterocyclic compounds, such as pyrazoles, imidazoles, and pyrimidines.
2. Cross-coupling reactions: The compound can be used as a ligand in cross-coupling reactions, such as Suzuki coupling, Stille coupling, and copper-catalyzed coupling.
3. Organocatalysis: 1,4-Dimethylpyrazole can be used as a catalyst or catalyst component in organocatalytic reactions, such as aminolysis, hydroamination, and hydroamination.

Case Studies

Here are two case studies showcasing the use of 1,4-Dimethylpyrazole in chemical reactions:

Case Study 1: Synthesis of Pyrazole Derivatives

Company A used 1,4-Dimethylpyrazole as a building block for the synthesis of pyrazole derivatives. The reaction involved a nucleophilic substitution reaction between 1,4-Dimethylpyrazole and an alkyl halide. The resulting pyrazole derivatives were further used in pharmaceutical applications.

Case Study 2: Suzuki Coupling Reaction

Company B employed 1,4-Dimethylpyrazole as a ligand in a Suzuki coupling reaction. The reaction involved the coupling of a boronic acid and a phenylboronic acid, resulting in the formation of a biaryl compound. This compound was further used in the synthesis of a pharmaceutical intermediate.

Solutions for Efficient Chemical Reactions

1,4-Dimethylpyrazole offers several solutions for efficient chemical reactions:

1. Enhanced reaction rates: The compound can accelerate the reaction rates in various chemical transformations, leading to higher yields and shorter reaction times.
2. Selectivity: 1,4-Dimethylpyrazole can be used to achieve high selectivity in specific chemical reactions, reducing the formation of by-products.
3. Versatility: The compound can be used in various reaction types, making it a versatile choice for chemical synthesis.

Expert Guidance

For optimal results, it is recommended to follow the following guidelines when using 1,4-Dimethylpyrazole:

1. Ensure the compound is stored in a cool, dry place away from direct sunlight.
2. Use appropriate solvents and reaction conditions for the desired chemical transformation.
3. Monitor the reaction progress and adjust the reaction conditions if necessary.

Conclusion

In conclusion, 1,4-Dimethylpyrazole CAS 1072-68-0 is a valuable organic compound for efficient chemical reactions. Its versatile nature, combined with its ability to enhance reaction rates and selectivity, makes it an ideal choice for various chemical transformations. By understanding the product's parameters, usage scenarios, and case studies, researchers and chemists can unlock advanced synthesis solutions for their chemical reactions.