Revolutionize Your Synthesis： D-TERT-LEUCINE HCl for Efficient Peptide Production

2025-3-21

Abstract

This article provides a comprehensive guide on Revolutionize Your Synthesis: D-TERT-LEUCINE HCl for Efficient Peptide Production. It outlines the product parameters, usage scenarios, case studies, solutions, expert guidance, and FAQs to help users understand and utilize this innovative peptide synthesis reagent effectively.

Product Parameters

The D-TERT-LEUCINE HCl is a high-purity, crystalline solid with a molecular formula of C6H13NO2·HCl. It has a melting point of 234-236°C and a pKa value of 2.2. The product is suitable for use in peptide synthesis, especially for the preparation of cyclic peptides and peptides containing D-amino acids.

Usage Scenarios

The D-TERT-LEUCINE HCl is widely used in various fields, including:

1. Peptide synthesis: The product is an excellent protecting group for the C-terminus of peptides, which can be easily removed by acid hydrolysis.
2. Cyclic peptide synthesis: The D-TERT-LEUCINE HCl can be used to synthesize cyclic peptides, which have unique biological activities.
3. D-amino acid-containing peptide synthesis: The product is suitable for the preparation of peptides containing D-amino acids, which have significant biological significance.

Case Studies

1. Company A: Company A used D-TERT-LEUCINE HCl to synthesize a cyclic peptide with high activity. The product significantly improved the yield and purity of the cyclic peptide, and the activity of the peptide was also enhanced.
2. Company B: Company B used D-TERT-LEUCINE HCl to synthesize a peptide containing D-amino acids. The product facilitated the synthesis process and improved the yield and purity of the peptide.

Solutions

1. High purity: The D-TERT-LEUCINE HCl has high purity, which ensures the quality of the synthesized peptides.
2. Easy removal: The protecting group of D-TERT-LEUCINE HCl can be easily removed by acid hydrolysis, simplifying the synthesis process.
3. Cost-effective: The product is cost-effective, making it an ideal choice for peptide synthesis.

Expert Guidance

1. Choose the appropriate solvent: The D-TERT-LEUCINE HCl is soluble in DCM, dichloromethane, and other organic solvents. It is recommended to use DCM or dichloromethane as the solvent for the synthesis process.
2. Control the reaction temperature: The reaction temperature should be controlled within the range of 0-10°C to ensure the stability of the product.
3. Optimize the reaction conditions: The reaction conditions, such as the molar ratio of reagents and the reaction time, should be optimized to improve the yield and purity of the synthesized peptides.

FAQs

1. Q: What is the melting point of D-TERT-LEUCINE HCl?
A: The melting point of D-TERT-LEUCINE HCl is 234-236°C.

2. Q: Can D-TERT-LEUCINE HCl be used for the synthesis of cyclic peptides?
A: Yes, D-TERT-LEUCINE HCl can be used for the synthesis of cyclic peptides, which have unique biological activities.

3. Q: How can I remove the protecting group of D-TERT-LEUCINE HCl?
A: The protecting group of D-TERT-LEUCINE HCl can be easily removed by acid hydrolysis.

Conclusion

Revolutionize Your Synthesis: D-TERT-LEUCINE HCl for Efficient Peptide Production is an innovative peptide synthesis reagent with high purity, easy removal, and cost-effectiveness. It is widely used in various fields, such as peptide synthesis, cyclic peptide synthesis, and D-amino acid-containing peptide synthesis. By following the expert guidance and FAQs provided in this article, users can effectively utilize this product to synthesize high-quality peptides.