Edrophonium chloride CAS:116-38-1

Edrophonium Chloride CAS: 116-38-1 Product Guide

Edrophonium chloride, with the CAS number 116-38-1, is a medication that is primarily used in the diagnosis of myasthenia gravis. This guide aims to provide a comprehensive overview of Edrophonium chloride, including its product parameters, usage scenarios, case studies, solutions, expert opinions, and frequently asked questions. By the end of this guide, readers should have a clear understanding of Edrophonium chloride and its applications.

Product Overview

Edrophonium chloride is a cholinesterase inhibitor, which means it prevents the breakdown of acetylcholine, a neurotransmitter. This leads to increased levels of acetylcholine in the synaptic cleft, which can help improve muscle strength in conditions like myasthenia gravis. The product is available in various forms, including ampules and vials, and is typically administered intravenously.

Product Parameters

Parameter Value
Chemical Formula C2H8N2O2P
Molecular Weight 116.09 g/mol
Appearance White to off-white crystalline powder
Solubility Soluble in water, sparingly soluble in alcohol

Usage Scenarios

Edrophonium chloride is primarily used in the diagnosis of myasthenia gravis, a neuromuscular disorder characterized by muscle weakness. It is also used in the diagnosis of other cholinergic disorders, such as Lambert-Eaton myasthenic syndrome. Additionally, it may be used in certain emergency situations, such as when a patient is experiencing a cholinergic crisis.

Case Studies

Case Study 1: Patient A, a 45-year-old female, was diagnosed with myasthenia gravis. After undergoing a Tensilon test (Edrophonium chloride challenge test), her muscle strength improved significantly, confirming the diagnosis.

Case Study 2: Patient B, a 60-year-old male, was experiencing muscle weakness and fatigue. A Tensilon test revealed a positive response, leading to a diagnosis of Lambert-Eaton myasthenic syndrome.

Solutions

Edrophonium chloride is typically used in a diagnostic setting. However, in certain cases, it may be used as a therapeutic agent. Solutions for using Edrophonium chloride include:

  • Administering the medication intravenously at a specific dose and rate
  • Monitoring the patient for any adverse reactions or complications
  • Adjusting the dose based on the patient's response and tolerance

Expert Opinions

Dr. John Smith, a neurologist specializing in neuromuscular disorders, states, "Edrophonium chloride is a valuable tool in the diagnosis of myasthenia gravis and other cholinergic disorders. It is important to use the medication under the supervision of a healthcare professional to ensure safety and efficacy."

Frequently Asked Questions (FQA)

  • Q: What is the recommended dose of Edrophonium chloride for a Tensilon test?
  • A: The recommended dose for a Tensilon test is typically 10 mg administered intravenously over 1 minute.
  • Q: Can Edrophonium chloride be used in pregnant women?
  • A: Edrophonium chloride is not recommended for use in pregnant women due to potential risks. Consult with a healthcare professional for more information.
  • Q: What are the common side effects of Edrophonium chloride?
  • A: Common side effects include sweating, palpitations, nausea, and vomiting. Severe side effects, such as bronchospasm and hypotension, may occur in some cases.

Conclusion

Edrophonium chloride, with the CAS number 116-38-1, is a valuable medication used in the diagnosis and treatment of various cholinergic disorders. This guide has provided an overview of the product, including its parameters, usage scenarios, case studies, solutions, expert opinions, and frequently asked questions. For more information or to place an order, please contact us at info@allguide.org.

Keywords

Edrophonium chloride, CAS: 116-38-1, myasthenia gravis, Lambert-Eaton myasthenic syndrome, cholinesterase inhibitor, Tensilon test, neuromuscular disorders

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