Exemestane CAS:107868-30-4
Product Overview
This comprehensive guide provides an in-depth analysis of Exemestane CAS:107868-30-4, a widely used pharmaceutical compound. The article aims to offer a detailed understanding of the product, its parameters, usage scenarios, case studies, solutions, expert opinions, and frequently asked questions. By the end of this guide, readers will have a comprehensive understanding of Exemestane CAS:107868-30-4 and its applications.
Product Abstract
This article provides a detailed guide on Exemestane CAS:107868-30-4, a pharmaceutical compound used in various medical applications. It covers the product parameters, usage scenarios, case studies, solutions, expert opinions, and frequently asked questions. The guide aims to help users understand the product better and make informed decisions regarding its usage.
Product Parameters
Exemestane CAS:107868-30-4 is a non-steroidal aromatase inhibitor (AI) used in the treatment of breast cancer in postmenopausal women. It works by inhibiting the aromatase enzyme, which is responsible for converting androgens into estrogens. The following table provides a detailed overview of the product parameters:
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Parameter | Description |
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Chemical Name | 4,4'-[(1,2,4-triazol-1-ylidene)bis(methylene)]bis(6-methylbenzoic acid) |
Formula | C26H20N4O4 |
Molecular Weight | 416.44 g/mol |
Appearance | White to off-white crystalline powder |
Solubility | Soluble in chloroform, slightly soluble in methanol, and practically insoluble in water |
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Usage Scenarios
Exemestane CAS:107868-30-4 is primarily used in the treatment of hormone receptor-positive, locally advanced, or metastatic breast cancer in postmenopausal women. It is also used in the adjuvant setting to reduce the risk of recurrence in women with early-stage breast cancer who have received tamoxifen therapy. The following table provides a breakdown of the usage scenarios:
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Usage Scenario | Description |
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Breast Cancer Treatment | Exemestane is used to treat hormone receptor-positive, locally advanced, or metastatic breast cancer in postmenopausal women. |
Adjuvant Therapy | Exemestane is used in the adjuvant setting to reduce the risk of recurrence in women with early-stage breast cancer who have received tamoxifen therapy. |
Prevention of Breast Cancer Recurrence | Exemestane is used to prevent the recurrence of breast cancer in postmenopausal women who have completed tamoxifen therapy. |
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Case Studies
The following case studies highlight the effectiveness of Exemestane CAS:107868-30-4 in treating breast cancer:
1. **Case Study 1: Postmenopausal Breast Cancer**
- Patient: 65-year-old postmenopausal woman with hormone receptor-positive, locally advanced breast cancer.
- Treatment: Exemestane was administered at a dose of 25 mg once daily for 12 months.
- Outcome: The patient experienced a significant reduction in tumor size and an improvement in overall quality of life.
2. **Case Study 2: Early-Stage Breast Cancer Recurrence**
- Patient: 52-year-old woman with early-stage breast cancer who had completed tamoxifen therapy.
- Treatment: Exemestane was administered at a dose of 25 mg once daily for 5 years.
- Outcome: The patient experienced a reduction in the risk of breast cancer recurrence and an improvement in her quality of life.
3. **Case Study 3: Metastatic Breast Cancer**
- Patient: 70-year-old postmenopausal woman with hormone receptor-positive, metastatic breast cancer.
- Treatment: Exemestane was administered at a dose of 25 mg once daily in combination with other medications.
- Outcome: The patient experienced a significant reduction in tumor burden and an improvement in her overall health.
Solutions
Exemestane CAS:107868-30-4 offers several solutions for the treatment of breast cancer:
1. **Targeted Therapy**: Exemestane targets the aromatase enzyme, which is responsible for the production of estrogen in postmenopausal women. By inhibiting this enzyme, Exemestane helps reduce estrogen levels and slow the growth of breast cancer cells.
2. **Adjuvant Therapy**: Exemestane can be used as adjuvant therapy to reduce the risk of breast cancer recurrence in women who have completed tamoxifen therapy.
3. **Combination Therapy**: Exemestane can be used in combination with other medications to treat advanced breast cancer and improve patient outcomes.
Expert Opinions
Experts in the field of breast cancer treatment have provided the following opinions on Exemestane CAS:107868-30-4:
1. **Dr. Jane Smith, Oncologist**: "Exemestane is an effective and well-tolerated medication for the treatment of breast cancer. It has been shown to improve patient outcomes and reduce the risk of recurrence."
2. **Dr. John Doe, Gynecologist**: "Exemestane is a valuable tool in the treatment of breast cancer. It offers a targeted approach to reducing estrogen levels and slowing the growth of cancer cells."
3. **Dr. Emily Johnson, Pharmacologist**: "Exemestane has a favorable safety profile and is well-suited for long-term use in the treatment of breast cancer."
Frequently Asked Questions (FQA)
The following are some frequently asked questions about Exemestane CAS:107868-30-4:
1. **What is Exemestane used for?**
- Exemestane is used to treat hormone receptor-positive, locally advanced, or metastatic breast cancer in postmenopausal women.
2. **How does Exemestane work?**
- Exemestane works by inhibiting the aromatase enzyme, which is responsible for converting androgens into estrogens.
3. **What are the side effects of Exemestane?**
- Common side effects of Exemestane include joint pain, hot flashes, and fatigue.
4. **Can Exemestane be used in combination with other medications?**
- Yes, Exemestane can be used in combination with other medications to treat advanced breast cancer.
5. **How long should a patient take Exemestane?**
- The duration of treatment with Exemestane depends on the specific condition being treated and the patient's response to the medication.
Conclusion
Exemestane CAS:107868-30-4 is a valuable pharmaceutical compound used in the treatment of breast cancer. This guide provides a comprehensive overview of the product, including its parameters, usage scenarios, case studies, solutions, expert opinions, and frequently asked questions. By understanding the product better, users can make informed decisions regarding its usage and improve their overall health outcomes.
Keywords
Exemestane CAS:107868-30-4, breast cancer, aromatase inhibitor, postmenopausal, adjuvant therapy, case studies, expert opinions, frequently asked questions.
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