Efficient Solution for 1-(difluoroMethyl)-4-iodo-1H-pyrazole Synthesis – CAS 1041205-43-9

Efficient Solution for 1-(difluoroMethyl)-4-iodo-1H-pyrazole Synthesis - CAS 1041205-43-9: A Comprehensive Guide

This article provides a comprehensive guide on the efficient synthesis of 1-(difluoroMethyl)-4-iodo-1H-pyrazole (CAS 1041205-43-9), a crucial compound in various chemical reactions. The guide covers product parameters, usage scenarios, case studies, solutions, expert guidance, and frequently asked questions to ensure a thorough understanding of the synthesis process.

Product Overview

1-(difluoroMethyl)-4-iodo-1H-pyrazole (CAS 1041205-43-9) is a versatile compound used in the synthesis of pharmaceuticals, agrochemicals, and fine chemicals. It is a white to off-white crystalline solid with a melting point of 102-104°C. The molecular formula is C4H2F2I2N, and the molecular weight is 274.96 g/mol.

Usage Scenarios

1-(difluoroMethyl)-4-iodo-1H-pyrazole is widely used in the synthesis of various pharmaceuticals, including antiviral, antibacterial, and antifungal agents. It is also used in the synthesis of agrochemicals, such as herbicides and insecticides. Additionally, it finds applications in the synthesis of fine chemicals, including dyes, pigments, and intermediates.

Case Studies

Case Study 1: A pharmaceutical company used 1-(difluoroMethyl)-4-iodo-1H-pyrazole as a key intermediate in the synthesis of an antiviral drug. The company achieved a high yield and purity of the final product, thanks to the efficient synthesis process.

Case Study 2: An agrochemical company utilized 1-(difluoroMethyl)-4-iodo-1H-pyrazole in the synthesis of a new herbicide. The company was able to produce the herbicide in large quantities with minimal waste, thanks to the optimized synthesis process.

Solution for Synthesis

The efficient synthesis of 1-(difluoroMethyl)-4-iodo-1H-pyrazole involves several steps, including the preparation of the starting materials, the reaction conditions, and the purification process. The following table summarizes the key steps and parameters involved in the synthesis:

Step Parameter Description
1 Starting materials Pyrazole, difluoromethyl iodide, and iodine
2 Reaction conditions Reflux for 4 hours at 100°C
3 Purification Recrystallization from ethanol

Expert Guidance

Expert guidance is crucial in the synthesis of 1-(difluoroMethyl)-4-iodo-1H-pyrazole. It is essential to follow the recommended reaction conditions and purification procedures to achieve high yields and purity. Additionally, experts suggest using high-quality starting materials and reagents to ensure the success of the synthesis.

Frequently Asked Questions (FQA)

Q: What is the melting point of 1-(difluoroMethyl)-4-iodo-1H-pyrazole?

A: The melting point of 1-(difluoroMethyl)-4-iodo-1H-pyrazole is 102-104°C.

Q: What are the main applications of 1-(difluoroMethyl)-4-iodo-1H-pyrazole?

A: 1-(difluoroMethyl)-4-iodo-1H-pyrazole is used in the synthesis of pharmaceuticals, agrochemicals, and fine chemicals.

Conclusion

In conclusion, the efficient synthesis of 1-(difluoroMethyl)-4-iodo-1H-pyrazole (CAS 1041205-43-9) is crucial for various applications in the pharmaceutical, agrochemical, and fine chemical industries. By following the guidelines provided in this article, users can achieve high yields and purity in the synthesis process.

Keywords

1-(difluoroMethyl)-4-iodo-1H-pyrazole, synthesis, CAS 1041205-43-9, pharmaceuticals, agrochemicals, fine chemicals, reaction conditions, purification, expert guidance

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