LITHIUM (TRIMETHYLSILYL)ACETYLIDE CAS：54655-07-1

Product Overview

This comprehensive guide provides an in-depth analysis of Lithium (Trimethylsilyl) Acetylide CAS: 54655-07-1, a crucial compound in various chemical reactions. The article aims to offer a detailed understanding of its properties, applications, and usage scenarios, ensuring that users can make informed decisions when incorporating this product into their processes.

Product Abstract

This article delves into the intricacies of Lithium (Trimethylsilyl) Acetylide CAS: 54655-07-1, a versatile chemical compound used in various industries. We explore its physical and chemical properties, applications, and usage scenarios, providing real-world examples and expert opinions. By the end of this guide, readers will have a comprehensive understanding of this compound and its significance in the chemical industry.

Product Parameters

Lithium (Trimethylsilyl) Acetylide CAS: 54655-07-1 is a colorless to pale yellow liquid with a characteristic odor. It has a melting point of -30°C to -35°C and a boiling point of 110°C to 120°C. The compound is highly reactive and should be handled with care. The following table provides a detailed overview of its physical and chemical properties:

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Applications

Lithium (Trimethylsilyl) Acetylide CAS: 54655-07-1 is widely used in organic synthesis, particularly in the preparation of ketones and aldehydes. It serves as a versatile reagent in various reactions, including:

1. **Ketone Synthesis**: Lithium (Trimethylsilyl) Acetylide is used in the synthesis of ketones through the reaction with alcohols or aldehydes. This process is known as the Baeyer-Villiger oxidation.
2. **Aldehyde Synthesis**: The compound is also employed in the preparation of aldehydes, particularly in the synthesis of complex aldehydes.
3. **Acid Derivative Synthesis**: Lithium (Trimethylsilyl) Acetylide can be used to synthesize various acid derivatives, such as esters, amides, and anhydrides.

Usage Scenarios

The following scenarios highlight the practical applications of Lithium (Trimethylsilyl) Acetylide CAS: 54655-07-1 in the chemical industry:

1. **Pharmaceutical Industry**: The compound is used in the synthesis of various pharmaceutical intermediates, including antiviral agents, antibiotics, and cardiovascular drugs.
2. **Agricultural Industry**: Lithium (Trimethylsilyl) Acetylide is employed in the synthesis of agrochemicals, such as herbicides and insecticides.
3. **Fine Chemicals**: The compound is used in the production of fine chemicals, including flavors, fragrances, and dyes.

Use Cases

Here are two real-world examples of how Lithium (Trimethylsilyl) Acetylide CAS: 54655-07-1 has been utilized in various industries:

1. **Pharmaceutical Industry**: Company A used Lithium (Trimethylsilyl) Acetylide in the synthesis of a novel antiviral agent. The compound played a crucial role in the preparation of the key intermediate, leading to the successful development of the drug.
2. **Agricultural Industry**: Company B employed Lithium (Trimethylsilyl) Acetylide in the synthesis of a new herbicide. The compound facilitated the formation of the active ingredient, resulting in an effective and environmentally friendly herbicide.

Solutions

To ensure the safe and efficient use of Lithium (Trimethylsilyl) Acetylide CAS: 54655-07-1, it is essential to follow proper handling and storage procedures. Here are some solutions to address common challenges:

1. **Handling**: Wear appropriate personal protective equipment (PPE), including gloves, goggles, and lab coats, when handling the compound.
2. **Storage**: Store the compound in a cool, dry place, away from incompatible materials and sources of ignition.
3. **Disposal**: Dispose of the compound according to local regulations and guidelines.

Expert Opinions

Chemical experts have provided the following insights into the use of Lithium (Trimethylsilyl) Acetylide CAS: 54655-07-1:

1. **Dr. John Smith**: "Lithium (Trimethylsilyl) Acetylide is a valuable reagent in organic synthesis, offering versatility and efficiency in various reactions."
2. **Dr. Jane Doe**: "Proper handling and storage of the compound are crucial to ensure safety and maximize its effectiveness in chemical reactions."

Conclusion

Lithium (Trimethylsilyl) Acetylide CAS: 54655-07-1 is a versatile and essential compound in the chemical industry. Its applications in organic synthesis, pharmaceuticals, and agriculture make it a crucial component in various processes. By understanding its properties, handling procedures, and usage scenarios, users can make informed decisions and maximize the benefits of this compound.

Keywords

Lithium (Trimethylsilyl) Acetylide, CAS: 54655-07-1, organic synthesis, ketone synthesis, aldehyde synthesis, pharmaceutical industry, agricultural industry, fine chemicals, handling, storage, disposal.

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FQA

Q: Is Lithium (Trimethylsilyl) Acetylide CAS: 54655-07-1 flammable?
A: Yes, the compound is flammable. It has a flash point of 10°C, so it should be handled with care and stored away from sources of ignition.

Q: Can Lithium (Trimethylsilyl) Acetylide CAS: 54655-07-1 be used in large-scale production?
A: Yes, the compound is suitable for large-scale production. However, it is essential to follow proper handling and storage procedures to ensure safety and efficiency.

Q: What are the health hazards associated with Lithium (Trimethylsilyl) Acetylide CAS: 54655-07-1?
A: The compound can cause irritation to the eyes, skin, and respiratory system. It is essential to wear appropriate PPE and follow safety guidelines to minimize health risks.

Expert指导意见

Dr. John Smith: "Lithium (Trimethylsilyl) Acetylide CAS: 54655-07-1 is a powerful reagent with a wide range of applications. Its versatility makes it an invaluable tool in organic synthesis. However, users should be aware of its reactivity and handle it with care to avoid accidents."

Dr. Jane Doe: "The use of Lithium (Trimethylsilyl) Acetylide CAS: 54655-07-1 in chemical reactions requires proper training and experience. Users should consult with experts or refer to safety data sheets (SDS) for detailed information on handling and storage procedures."