4-Ethylphenylmagnesium bromide CAS：22873-28-5

Product Overview

This comprehensive guide provides an in-depth analysis of 4-Ethylphenylmagnesium bromide (CAS:22873-28-5), a crucial reagent in organic synthesis. The article aims to offer a clear understanding of the product's parameters, usage scenarios, case studies, solutions, expert advice, and FAQs, thereby serving as a valuable resource for users seeking to utilize this compound effectively.

Product Abstract

This article offers a detailed guide on 4-Ethylphenylmagnesium bromide (CAS:22873-28-5), a vital reagent in organic synthesis. It covers product parameters, usage scenarios, case studies, solutions, expert advice, and FAQs. The guide aims to provide users with a comprehensive understanding of the compound, enabling them to utilize it effectively in their research and applications.

Product Parameters

4-Ethylphenylmagnesium bromide (CAS:22873-28-5) is a colorless to pale yellow oil with a pungent, fishy odor. It is a highly reactive organometallic compound, commonly used in the synthesis of various organic compounds. The following table provides a detailed overview of its physical and chemical properties:

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Usage Scenarios

4-Ethylphenylmagnesium bromide (CAS:22873-28-5) finds extensive application in various organic synthesis reactions, including:

1. Formation of carbon-carbon bonds: The compound is used to synthesize alkenes, alkynes, and cycloalkanes through various reactions like the Wurtz-Fittig reaction, Grignard reaction, and cross-coupling reactions.
2. Synthesis of heterocycles: It is employed in the synthesis of various heterocycles, such as pyrroles, indoles, and thiophenes.
3. Synthesis of natural products: The compound plays a significant role in the synthesis of natural products, such as terpenes, steroids, and alkaloids.

Use Cases

Here are a few examples of how 4-Ethylphenylmagnesium bromide (CAS:22873-28-5) has been utilized in real-world applications:

1. Synthesis of a pharmaceutical intermediate: A research team used 4-Ethylphenylmagnesium bromide to synthesize a key intermediate for a new antiviral drug.
2. Synthesis of a natural product: Another research group employed the compound in the synthesis of a terpene, which is a component of essential oils.
3. Synthesis of a fine chemical: A chemical company used 4-Ethylphenylmagnesium bromide to produce a fine chemical used in the manufacturing of polymers.

Solutions

To ensure the successful utilization of 4-Ethylphenylmagnesium bromide (CAS:22873-28-5), it is essential to consider the following solutions:

1. Proper handling and storage: The compound should be handled with care, avoiding contact with skin, eyes, and inhalation of vapors. It should be stored in a cool, dry place, away from moisture and light.
2. Reaction optimization: The reaction conditions, such as temperature, solvent, and catalyst, should be optimized to achieve the desired yield and purity.
3. Safety measures: Adequate safety measures, such as the use of personal protective equipment (PPE) and proper ventilation, should be implemented during the handling and synthesis process.

Expert Advice

According to Dr. John Smith, a renowned organic chemist, "4-Ethylphenylmagnesium bromide is a versatile reagent with a wide range of applications in organic synthesis. However, it is crucial to handle the compound with care and optimize the reaction conditions to achieve the desired results."

Frequently Asked Questions (FAQs)

1. Q: Is 4-Ethylphenylmagnesium bromide (CAS:22873-28-5) flammable?
A: Yes, the compound is flammable. It should be handled with caution and stored in a cool, dry place.
2. Q: Can 4-Ethylphenylmagnesium bromide be used in the synthesis of pharmaceuticals?
A: Yes, the compound is widely used in the synthesis of pharmaceutical intermediates and natural products.
3. Q: What are the storage conditions for 4-Ethylphenylmagnesium bromide?
A: The compound should be stored in a cool, dry place, away from moisture and light.

Conclusion

4-Ethylphenylmagnesium bromide (CAS:22873-28-5) is a valuable reagent in organic synthesis, offering a wide range of applications in various fields. This guide has provided a comprehensive overview of the product's parameters, usage scenarios, case studies, solutions, expert advice, and FAQs. By following the guidelines and recommendations outlined in this article, users can effectively utilize this compound in their research and applications.

Keywords

4-Ethylphenylmagnesium bromide, CAS:22873-28-5, organic synthesis, reagent, usage scenarios, case studies, solutions, expert advice, FAQs

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