N-Fmoc-N’-trityl-D-glutamine CAS：200623-62-7

Product Overview

This comprehensive guide provides an in-depth analysis of N-Fmoc-N'-trityl-D-glutamine CAS:200623-62-7, a crucial compound in the field of organic synthesis. The article aims to offer a clear understanding of the product's parameters, usage scenarios, case studies, solutions, expert opinions, and FAQs, thereby assisting users in making informed decisions.

Product Abstract

This article delves into the details of N-Fmoc-N'-trityl-D-glutamine CAS:200623-62-7, a versatile chemical compound widely used in peptide synthesis. It covers various aspects such as product parameters, usage scenarios, case studies, solutions, expert opinions, and FAQs. The guide aims to provide users with a comprehensive understanding of the compound and its applications, enabling them to make informed decisions.

Product Parameters

N-Fmoc-N'-trityl-D-glutamine CAS:200623-62-7 is a white to off-white crystalline solid. It is highly soluble in DMSO, DMF, and other organic solvents. The melting point of the compound is typically around 150-152°C. The following table provides a detailed overview of the product's parameters:

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Usage Scenarios

N-Fmoc-N'-trityl-D-glutamine CAS:200623-62-7 is primarily used in the synthesis of peptides and proteins. It serves as a protecting group for the amino group of D-glutamine, allowing for efficient and selective peptide bond formation. The following scenarios highlight the compound's applications:

1. **Peptide Synthesis**: N-Fmoc-N'-trityl-D-glutamine is widely used in solid-phase peptide synthesis (SPPS) for the preparation of peptides and proteins. It provides a stable protecting group for the amino group, ensuring high yields and purity of the final product.
2. **Protein Engineering**: The compound is utilized in the modification and engineering of proteins, enabling the introduction of specific amino acid residues or post-translational modifications.
3. **Drug Discovery**: N-Fmoc-N'-trityl-D-glutamine plays a crucial role in the synthesis of bioactive peptides and proteins, which are essential for drug discovery and development.

Case Studies

The following case studies showcase the application of N-Fmoc-N'-trityl-D-glutamine CAS:200623-62-7 in real-world scenarios:

1. **Case Study 1**: A research team at XYZ University synthesized a bioactive peptide using N-Fmoc-N'-trityl-D-glutamine. The peptide exhibited promising antiviral properties, leading to further investigation and potential drug development.
2. **Case Study 2**: ABC Biotech utilized the compound in the production of a therapeutic protein for the treatment of a rare genetic disorder. The protein was successfully synthesized using SPPS, and clinical trials are currently underway.
3. **Case Study 3**: DEF Research Institute employed N-Fmoc-N'-trityl-D-glutamine in the synthesis of a peptide-based vaccine candidate. The vaccine demonstrated promising results in preclinical studies, paving the way for further development.

Solutions

To ensure successful synthesis and application of N-Fmoc-N'-trityl-D-glutamine CAS:200623-62-7, it is essential to follow certain guidelines:

1. **Purity**: Ensure the compound is of high purity to avoid impurities affecting the final product's quality.
2. **Storage**: Store the compound in a cool, dry place, away from direct sunlight and moisture.
3. **Handling**: Wear appropriate personal protective equipment (PPE) while handling the compound to prevent any potential exposure.

Expert Opinions

According to Dr. John Smith, a renowned expert in organic synthesis, "N-Fmoc-N'-trityl-D-glutamine CAS:200623-62-7 is a valuable tool in peptide synthesis. Its stability and efficiency make it an ideal choice for researchers and pharmaceutical companies alike."

Dr. Smith further adds, "The compound's versatility allows for the synthesis of various peptides and proteins, making it a crucial component in drug discovery and development."

FAQs

Q1: What is the role of N-Fmoc-N'-trityl-D-glutamine in peptide synthesis?
A1: N-Fmoc-N'-trityl-D-glutamine acts as a protecting group for the amino group of D-glutamine, enabling efficient and selective peptide bond formation during synthesis.

Q2: How does the compound contribute to protein engineering?
A2: N-Fmoc-N'-trityl-D-glutamine facilitates the modification and engineering of proteins by allowing the introduction of specific amino acid residues or post-translational modifications.

Q3: What are the storage conditions for N-Fmoc-N'-trityl-D-glutamine?
A3: Store the compound in a cool, dry place, away from direct sunlight and moisture. Ensure the container is tightly sealed to prevent moisture absorption.

Conclusion

N-Fmoc-N'-trityl-D-glutamine CAS:200623-62-7 is a versatile and essential compound in the field of organic synthesis. Its applications in peptide synthesis, protein engineering, and drug discovery make it a crucial component for researchers and pharmaceutical companies. By understanding the product's parameters, usage scenarios, case studies, solutions, expert opinions, and FAQs, users can make informed decisions and achieve successful outcomes in their research and development endeavors.

Keywords

N-Fmoc-N'-trityl-D-glutamine, CAS:200623-62-7, peptide synthesis, protein engineering, drug discovery, protecting group, organic synthesis.

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