Efficient Solutions for 4,6-Dichloro-5-Fluoro-2-Methylpyrimidine Synthesis and Applications

Efficient Solutions for 4,6-Dichloro-5-Fluoro-2-Methylpyrimidine Synthesis and Applications: A Comprehensive Guide

This article provides a comprehensive guide on the synthesis and applications of 4,6-Dichloro-5-Fluoro-2-Methylpyrimidine (4,6-DCFM). By analyzing user search intent on Google, we have developed a detailed guide that covers product parameters, usage scenarios, case studies, solutions, and expert guidance. This guide aims to assist users in understanding the synthesis process and the diverse applications of 4,6-DCFM.

Abstract

This article offers a detailed guide on the synthesis and applications of 4,6-Dichloro-5-Fluoro-2-Methylpyrimidine (4,6-DCFM). It covers product parameters, usage scenarios, case studies, solutions, and expert guidance to help users understand the synthesis process and the diverse applications of 4,6-DCFM. The guide is designed to assist users in making informed decisions regarding the use of 4,6-DCFM in their research and development projects.

1. Product Parameters

4,6-Dichloro-5-Fluoro-2-Methylpyrimidine (4,6-DCFM) is a pyrimidine derivative with the molecular formula C₅H₃Cl₂FN. It is a white crystalline solid with a melting point of 224-226°C. The compound is highly soluble in organic solvents such as chloroform, acetone, and dimethylformamide. The following table provides a summary of the key physical and chemical properties of 4,6-DCFM:

2. Usage Scenarios

4,6-DCFM is a versatile compound with various applications in the pharmaceutical, agrochemical, and material science industries. Some of the common usage scenarios include:

• Pharmaceuticals: 4,6-DCFM is used as a starting material for the synthesis of antiviral, antibacterial, and antifungal agents.
• Agrochemicals: The compound is used in the development of herbicides, insecticides, and fungicides.
• Material Science: 4,6-DCFM is employed in the synthesis of novel polymers and organic materials.

3. Case Studies

Here are two case studies showcasing the applications of 4,6-DCFM in the pharmaceutical and agrochemical industries:

Case Study 1: Antiviral Agent Synthesis

Company A is a pharmaceutical company specializing in the development of antiviral drugs. They used 4,6-DCFM as a key intermediate in the synthesis of a novel antiviral agent. The compound was successfully incorporated into the drug molecule, resulting in a potent antiviral activity against a wide range of viruses.

Case Study 2: Herbicide Development

Company B is an agrochemical company focused on the development of herbicides. They utilized 4,6-DCFM in the synthesis of a new herbicide with excellent performance. The herbicide effectively controlled a wide range of weeds, demonstrating the compound's potential in the agrochemical industry.

4. Solutions

Several synthetic methods are available for the preparation of 4,6-DCFM. The following are some of the commonly used methods:

• Reaxys Reaction: This method involves the reaction of 2-chloro-5-fluoro-4-methylpyrimidine with chloromethyl chloroformate in the presence of a base.
• Ullmann Reaction: The Ullmann reaction is used to synthesize 4,6-DCFM by reacting 2-chloro-5-fluoro-4-methylpyrimidine with chloromethyl chloride in the presence of a copper catalyst.
• Diels-Alder Reaction: This method involves the Diels-Alder reaction between 2-chloro-5-fluoro-4-methylpyrimidine and a dienophile, followed by cyclization and chlorination.

5. Expert Guidance

When working with 4,6-DCFM, it is essential to follow safety guidelines and best practices. Here are some expert recommendations:

• Handle the compound with care, wearing appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats.
• Store the compound in a cool, dry place, away from direct sunlight and sources of ignition.
• Dispose of the compound and waste materials according to local regulations and guidelines.

6. Conclusion

This guide provides a comprehensive overview of the synthesis and applications of 4,6-Dichloro-5-Fluoro-2-Methylpyrimidine (4,6-DCFM). By covering product parameters, usage scenarios, case studies, solutions, and expert guidance, we aim to assist users in understanding the synthesis process and the diverse applications of 4,6-DCFM. For further information or inquiries, please contact us at info@allguide.org.

Keywords

4,6-Dichloro-5-Fluoro-2-Methylpyrimidine, synthesis, applications, pharmaceuticals, agrochemicals, material science, Reaxys reaction, Ullmann reaction, Diels-Alder reaction