Efficient Solutions for 3-Bromo-6-chloropicolinonitrile Synthesis – 97% Pure CAS 1053659-39-4

Efficient Solutions for 3-Bromo-6-chloropicolinonitrile Synthesis - 97% Pure CAS 1053659-39-4

This comprehensive guide provides an in-depth analysis of the synthesis of 3-Bromo-6-chloropicolinonitrile (CAS 1053659-39-4), a high-purity chemical compound with numerous applications. The article aims to offer practical solutions and insights into the synthesis process, usage scenarios, and real-world case studies. By the end of this guide, readers will have a comprehensive understanding of the product and its applications.

Product Overview

3-Bromo-6-chloropicolinonitrile, with the chemical formula C7H3BrClN2, is a white crystalline solid. It is a key intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other organic compounds. The product is available in 97% purity, ensuring high-quality and reliable performance in various applications.

Product Parameters

Usage Scenarios

3-Bromo-6-chloropicolinonitrile finds extensive applications in the pharmaceutical industry, particularly in the synthesis of antiviral, antibacterial, and antifungal agents. It is also used in the agrochemical sector for the development of herbicides, insecticides, and fungicides. Additionally, the compound is employed in the synthesis of dyes, pigments, and other organic intermediates.

Case Studies

1. Pharmaceutical Industry: Company A, a leading pharmaceutical manufacturer, utilizes 3-Bromo-6-chloropicolinonitrile in the synthesis of a novel antiviral drug. The high purity of the compound ensures the drug's efficacy and safety, contributing to the company's success in the market.

2. Agrochemical Industry: Company B, a renowned agrochemical producer, incorporates 3-Bromo-6-chloropicolinonitrile in the development of a new herbicide. The compound's effectiveness in controlling weeds and its environmental friendliness make it a valuable addition to the company's product line.

Solution for Synthesis

Several methods can be employed for the synthesis of 3-Bromo-6-chloropicolinonitrile. The most common methods include the nitration of picolinic acid, followed by bromination and chlorination. The following steps outline a typical synthesis process:

1. Nitration of picolinic acid: Picolinic acid is nitrated using a mixture of nitric acid and sulfuric acid to form 6-nitropicolinic acid.
2. Bromination: 6-Nitropicolinic acid is brominated using N-bromosuccinimide (NBS) in the presence of a base to yield 3-bromo-6-nitropicolinic acid.
3. Chlorination: 3-Bromo-6-nitropicolinic acid is chlorinated using thionyl chloride in the presence of a base to obtain 3-bromo-6-chloropicolinonitrile.

Expert Guidance

When synthesizing 3-Bromo-6-chloropicolinonitrile, it is crucial to follow safety guidelines and use appropriate equipment. Experts recommend the following precautions:

• Wear appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats.
• Work in a well-ventilated area or under a fume hood.
• Handle chemicals with care and avoid contact with skin and eyes.
• Dispose of waste materials according to local regulations.

Conclusion

3-Bromo-6-chloropicolinonitrile is a versatile and valuable chemical intermediate with numerous applications in various industries. This guide has provided an overview of the product, its parameters, usage scenarios, and synthesis process. By following the expert guidance and safety precautions, users can ensure successful synthesis and utilization of this compound.

Keywords

3-Bromo-6-chloropicolinonitrile, synthesis, CAS 1053659-39-4, pharmaceutical, agrochemical, intermediate, purity, safety, application

For more information or to place an order, please contact us at info@allguide.org.