Efficient Synthesis Aid： 6-Bromo-3-butoxy-2-fluorophenylboronic Acid for Chemo Selectivity

2025-3-21

Efficient Synthesis Aid: 6-Bromo-3-butoxy-2-fluorophenylboronic Acid for Chemo Selectivity

This comprehensive guide aims to provide an in-depth understanding of 6-Bromo-3-butoxy-2-fluorophenylboronic Acid, an efficient synthesis aid for achieving chemo selectivity. By analyzing its parameters, usage scenarios, case studies, and expert guidance, this article will serve as a valuable resource for users seeking to optimize their chemical synthesis processes.

Abstract

This article offers a detailed overview of 6-Bromo-3-butoxy-2-fluorophenylboronic Acid, a crucial synthesis aid for achieving chemo selectivity. By exploring its parameters, usage scenarios, case studies, and expert guidance, this guide aims to assist users in optimizing their chemical synthesis processes. With a focus on real-world applications and expert insights, this article serves as a valuable resource for chemists and researchers in the field.

Product Parameters

6-Bromo-3-butoxy-2-fluorophenylboronic Acid is a white to off-white crystalline solid with a melting point of 123-125°C. It is highly soluble in organic solvents such as dichloromethane, chloroform, and acetone. The molecular formula of this compound is C₁₂H₁₀BrFO₂B, and its molecular weight is 311.15 g/mol. The following table provides a summary of its key physical and chemical properties:

Property	Value
Molecular Formula	C₁₂H₁₀BrFO₂B
Molecular Weight	311.15 g/mol
Melting Point	123-125°C
Solubility	Organic Solvents: Dichloromethane, Chloroform, Acetone

Usage Scenarios

6-Bromo-3-butoxy-2-fluorophenylboronic Acid is widely used in the synthesis of chemo-selective compounds, particularly in the pharmaceutical industry. Its unique structure and properties make it an ideal choice for the following applications:

Medicinal Chemistry: The compound can be used as a building block for the synthesis of chemo-selective drugs, which are crucial for targeting specific cancer cells while minimizing damage to healthy cells.
Organic Synthesis: It serves as a versatile intermediate in the synthesis of various organic compounds, including heterocycles and bioactive molecules.
Pharmaceutical Development: The compound can be employed in the development of novel therapeutic agents with improved selectivity and efficacy.

Case Studies

Here are two real-world case studies showcasing the application of 6-Bromo-3-butoxy-2-fluorophenylboronic Acid in chemical synthesis:

Case Study 1: Synthesis of a Chemo-Selective Drug

Company A, a pharmaceutical company specializing in cancer research, aimed to synthesize a chemo-selective drug targeting a specific cancer type. By utilizing 6-Bromo-3-butoxy-2-fluorophenylboronic Acid as a key intermediate, the company successfully synthesized the desired compound with high purity and selectivity. This resulted in a significant reduction in side effects and improved patient outcomes.

Case Study 2: Synthesis of a Bioactive Molecule

Company B, a biotech firm focused on the development of natural products, sought to synthesize a bioactive molecule with potential therapeutic applications. By incorporating 6-Bromo-3-butoxy-2-fluorophenylboronic Acid into the synthesis process, the company achieved a high yield and purity of the target molecule, paving the way for further research and development.

Solution

6-Bromo-3-butoxy-2-fluorophenylboronic Acid offers a unique solution for achieving chemo selectivity in chemical synthesis. Its versatile nature and high purity make it an ideal choice for various applications, including medicinal chemistry, organic synthesis, and pharmaceutical development. By utilizing this compound, researchers and chemists can optimize their synthesis processes, resulting in improved selectivity and efficiency.

Expert Guidance

When working with 6-Bromo-3-butoxy-2-fluorophenylboronic Acid, it is essential to follow expert guidance to ensure safe and effective usage. Here are some key points to consider:

Handling: Wear appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats when handling the compound.
Storage: Store the compound in a cool, dry place away from direct sunlight and incompatible materials.
Handling of Reagents: Always use fresh, high-purity reagents to minimize the risk of impurities affecting the synthesis process.
Scale-up: When scaling up the synthesis process, carefully optimize reaction conditions and equipment to maintain selectivity and yield.

Conclusion

6-Bromo-3-butoxy-2-fluorophenylboronic Acid is a valuable synthesis aid for achieving chemo selectivity in chemical synthesis. Its unique structure and properties make it an ideal choice for various applications, including medicinal chemistry, organic synthesis, and pharmaceutical development. By following expert guidance and utilizing this compound, researchers and chemists can optimize their synthesis processes, resulting in improved selectivity and efficiency.