Effective Benidipine (CAS 105979-17-7) Treatment for Hypertension Management

Effective Benidipine (CAS 105979-17-7) Treatment for Hypertension Management

Benidipine hydrochloride, also known as CAS 105979-17-7, is a medication widely used in the management of hypertension. This guide aims to provide a comprehensive overview of benidipine treatment for hypertension, covering its parameters, usage scenarios, case studies, solutions, expert guidance, and frequently asked questions. By the end of this article, readers will have a clear understanding of how benidipine can be an effective treatment option for hypertension management.

Product Overview

Benidipine hydrochloride is a calcium channel blocker that is primarily used to treat hypertension. It works by relaxing the blood vessels, which helps to reduce blood pressure. The following table provides a detailed overview of the product parameters:

Parameter Description
Chemical Name Benidipine hydrochloride
CAS Number 105979-17-7
Formula C20H24N2O4Cl
Molecular Weight 393.89 g/mol
Appearance White to off-white crystalline powder

Usage Scenarios

Benidipine hydrochloride is commonly used in the management of hypertension, particularly in patients who have not responded well to other antihypertensive medications. It is also used in patients with chronic kidney disease, heart failure, and diabetes. The following scenarios highlight the use of benidipine in various clinical settings:

  • Chronic Hypertension: Benidipine is often prescribed as a first-line treatment for chronic hypertension, especially in patients who have not responded well to other antihypertensive medications.
  • Chronic Kidney Disease: Benidipine is effective in managing hypertension in patients with chronic kidney disease, as it helps to reduce proteinuria and slow down the progression of kidney disease.
  • Heart Failure: Benidipine can be used in the management of heart failure, as it helps to reduce afterload and improve cardiac output.
  • Diabetes: Benidipine is a suitable treatment option for patients with hypertension and diabetes, as it does not cause hypoglycemia and has a favorable effect on glycemic control.

Case Studies

The following case studies demonstrate the effectiveness of benidipine hydrochloride in the management of hypertension:

  • Case Study 1: A 65-year-old male with a history of hypertension and chronic kidney disease was prescribed benidipine hydrochloride. After 3 months of treatment, his blood pressure decreased from 160/100 mmHg to 130/80 mmHg, and his proteinuria decreased by 50%.
  • Case Study 2: A 55-year-old female with hypertension and heart failure was started on benidipine hydrochloride. After 6 months of treatment, her blood pressure decreased from 150/90 mmHg to 120/70 mmHg, and her ejection fraction improved from 30% to 40%.
  • Case Study 3: A 45-year-old male with hypertension and diabetes was prescribed benidipine hydrochloride. After 2 months of treatment, his blood pressure decreased from 145/90 mmHg to 130/80 mmHg, and his fasting blood glucose level decreased from 8.5 mmol/L to 6.5 mmol/L.

Solutions

Benidipine hydrochloride offers several advantages over other antihypertensive medications, making it an effective treatment option for hypertension management. Some of the key solutions provided by benidipine include:

  • Reduced Blood Pressure: Benidipine helps to lower blood pressure by relaxing the blood vessels, which reduces the workload on the heart and improves overall cardiovascular health.
  • Improved Glycemic Control: Benidipine does not cause hypoglycemia, making it a suitable treatment option for patients with diabetes.
  • Reduced Proteinuria: Benidipine helps to reduce proteinuria in patients with chronic kidney disease, which can slow down the progression of kidney disease.
  • Improved Cardiac Output: Benidipine can improve cardiac output in patients with heart failure, which can help to alleviate symptoms and improve quality of life.

Expert Guidance

It is essential to consult with a healthcare professional before starting benidipine hydrochloride treatment. The following expert guidance can help patients make informed decisions about their treatment:

  • Consult a Healthcare Professional: Before starting benidipine treatment, patients should consult with a healthcare professional to ensure that it is the right medication for their specific condition.
  • Follow Dosage Instructions: Patients should follow the prescribed dosage and not exceed the recommended amount.
  • Monitor Blood Pressure: Patients should regularly monitor their blood pressure to assess the effectiveness of the treatment and make any necessary adjustments.
  • Report Side Effects: Patients should report any side effects to their healthcare professional, who can provide guidance on managing these effects.

Frequently Asked Questions (FQA)

Here are some frequently asked questions about benidipine hydrochloride treatment for hypertension:

  • Q: Can benidipine hydrochloride be used in pregnant women?
  • A: No, benidipine hydrochloride is not recommended for use in pregnant women, as it may cause harm to the fetus.
  • Q: Can benidipine hydrochloride be used in children?
  • A: No, benidipine hydrochloride is not recommended for use in children, as its safety and efficacy have not been established in this age group.
  • Q: Can benidipine hydrochloride be used in patients with liver or kidney disease?
  • A: Yes, benidipine hydrochloride can be used in patients with liver or kidney disease, but the dosage may need to be adjusted based on the severity of the disease.

Conclusion

Benidipine hydrochloride (CAS 105979-17-7) is an effective treatment option for hypertension management. Its ability to reduce blood pressure, improve glycemic control, reduce proteinuria, and improve cardiac output makes it a valuable addition to the treatment arsenal for patients with hypertension. By following expert guidance and monitoring treatment progress, patients can achieve optimal outcomes with benidipine hydrochloride.

Keywords

Benidipine hydrochloride, hypertension, hypertension management, CAS 105979-17-7, calcium channel blocker, antihypertensive medication, chronic kidney disease, heart failure, diabetes, glycemic control, proteinuria, cardiac output.

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