Efficient Synthesis Aid: N-BOC-3-Iodo-L-Alanine Benzyl Ester for Peptide Modifications

Efficient Synthesis Aid: N-BOC-3-Iodo-L-Alanine Benzyl Ester for Peptide Modifications

This comprehensive guide aims to provide an in-depth understanding of N-BOC-3-Iodo-L-Alanine Benzyl Ester, an essential synthesis aid for peptide modifications. The article delves into various aspects such as product parameters, usage scenarios, case studies, solutions, expert guidance, and frequently asked questions (FAQs) to ensure a comprehensive understanding of the product.

Abstract

This guide offers a detailed overview of N-BOC-3-Iodo-L-Alanine Benzyl Ester, a key synthesis aid for peptide modifications. It covers product parameters, usage scenarios, case studies, solutions, expert guidance, and FAQs to provide a comprehensive understanding of the product's applications and benefits.

Product Parameters

N-BOC-3-Iodo-L-Alanine Benzyl Ester is a versatile synthesis aid used in peptide modifications. It is characterized by the following parameters:

Parameter Value
Chemical Formula C14H18N2O4I
Molecular Weight 318.28 g/mol
Appearance White to off-white crystalline powder
Purity ≥98%

Usage Scenarios

N-BOC-3-Iodo-L-Alanine Benzyl Ester is widely used in various peptide synthesis applications, including:

  • Site-specific modification of peptides
  • Introduction of iodo groups for radiolabeling
  • Construction of disulfide bonds in peptides

Case Studies

Here are two case studies showcasing the use of N-BOC-3-Iodo-L-Alanine Benzyl Ester in peptide modifications:

Case Study 1: Site-specific Modification of Peptides

Company A used N-BOC-3-Iodo-L-Alanine Benzyl Ester to modify a peptide with a specific amino acid residue. The modified peptide was successfully synthesized and characterized, demonstrating the effectiveness of the synthesis aid.

Case Study 2: Introduction of Iodo Groups for Radiolabeling

Company B employed N-BOC-3-Iodo-L-Alanine Benzyl Ester to introduce iodo groups into a peptide for radiolabeling purposes. The radiolabeled peptide was successfully synthesized and utilized in a research study, highlighting the product's applicability in radiolabeling.

Solutions

N-BOC-3-Iodo-L-Alanine Benzyl Ester offers several solutions for peptide modifications:

  • Enhanced efficiency in peptide synthesis
  • Improved purity and yield of modified peptides
  • Reduced reaction time and cost

Expert Guidance

For optimal results when using N-BOC-3-Iodo-L-Alanine Benzyl Ester, consider the following expert guidance:

  • Follow the recommended reaction conditions and stoichiometry
  • Use appropriate solvents and reagents
  • Monitor the reaction progress using suitable analytical techniques

Frequently Asked Questions (FAQs)

Q: What is the shelf life of N-BOC-3-Iodo-L-Alanine Benzyl Ester?

A: The shelf life of N-BOC-3-Iodo-L-Alanine Benzyl Ester is 2 years when stored in a cool, dry place away from direct sunlight.

Q: Can N-BOC-3-Iodo-L-Alanine Benzyl Ester be used for the synthesis of cyclic peptides?

A: Yes, N-BOC-3-Iodo-L-Alanine Benzyl Ester can be used for the synthesis of cyclic peptides, but it is essential to optimize the reaction conditions for successful synthesis.

Conclusion

N-BOC-3-Iodo-L-Alanine Benzyl Ester is a valuable synthesis aid for peptide modifications, offering numerous benefits such as enhanced efficiency, improved purity, and reduced reaction time. By understanding its usage scenarios, case studies, solutions, and expert guidance, researchers and scientists can effectively utilize this product in their peptide synthesis endeavors.

Keywords

N-BOC-3-Iodo-L-Alanine Benzyl Ester, peptide modifications, synthesis aid, radiolabeling, cyclic peptides

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