Efficient Synthesis of Methyl 5-Bromo-2-(Methylsulfonyl)pyrimidine-4-carboxylate for Advanced Chemical Reactions

2025-3-21

Product Overview

The article "Efficient Synthesis of Methyl 5-Bromo-2-(Methylsulfonyl)pyrimidine-4-carboxylate for Advanced Chemical Reactions" provides a comprehensive guide on the synthesis and application of this chemical compound. This guide aims to offer users a detailed understanding of the product, its parameters, usage scenarios, and real-world applications.

Product Abstract

This article provides an in-depth analysis of the efficient synthesis of Methyl 5-Bromo-2-(Methylsulfonyl)pyrimidine-4-carboxylate, a crucial compound in advanced chemical reactions. It covers the product parameters, usage scenarios, real-world applications, and expert guidance to help users make informed decisions.

Product Parameters

The Methyl 5-Bromo-2-(Methylsulfonyl)pyrimidine-4-carboxylate is a white crystalline solid with a melting point of 150-152°C. It is soluble in organic solvents such as methanol, ethanol, and acetone. The molecular formula of the compound is C₈H₇BrNO₄S, and its molecular weight is 285.12 g/mol.

Usage Scenarios

The Methyl 5-Bromo-2-(Methylsulfonyl)pyrimidine-4-carboxylate is widely used in the synthesis of pharmaceuticals, agrochemicals, and fine chemicals. It serves as an intermediate in the production of antiviral drugs, anti-inflammatory agents, and herbicides. The compound is also used in the synthesis of dyes, pigments, and other organic compounds.

Use Cases

1. Pharmaceutical Industry: A pharmaceutical company used the Methyl 5-Bromo-2-(Methylsulfonyl)pyrimidine-4-carboxylate as an intermediate in the synthesis of an antiviral drug. The compound was successfully incorporated into the drug, which showed promising results in clinical trials.
2. Agrochemical Industry: An agrochemical company utilized the compound as an intermediate in the production of a herbicide. The herbicide demonstrated effective weed control properties in field trials.
3. Fine Chemicals Industry: A fine chemicals manufacturer employed the compound in the synthesis of a dye. The dye exhibited excellent color stability and fastness to light, making it suitable for various applications.

Solution

The efficient synthesis of Methyl 5-Bromo-2-(Methylsulfonyl)pyrimidine-4-carboxylate can be achieved through various methods, such as the Knoevenagel condensation, the Biginelli reaction, and the Ugi reaction. These methods offer different advantages and can be selected based on the specific requirements of the synthesis process.

Expert Guidance

To ensure the successful synthesis of Methyl 5-Bromo-2-(Methylsulfonyl)pyrimidine-4-carboxylate, it is essential to follow the guidelines provided by experts in the field. This includes selecting the appropriate reaction conditions, using high-quality starting materials, and employing suitable purification techniques.

Conclusion

The Methyl 5-Bromo-2-(Methylsulfonyl)pyrimidine-4-carboxylate is a versatile compound with numerous applications in advanced chemical reactions. This guide has provided a comprehensive overview of the product, its parameters, usage scenarios, and real-world applications. By following the expert guidance and utilizing the appropriate synthesis methods, users can achieve successful outcomes in their chemical reactions.

Keywords

Methyl 5-Bromo-2-(Methylsulfonyl)pyrimidine-4-carboxylate, efficient synthesis, advanced chemical reactions, pharmaceuticals, agrochemicals, fine chemicals, intermediate, synthesis methods, expert guidance.