Efficient Synthesis Aid: (2-Chloropyridin-3-yl)acetonitrile for Complex Reactions

Efficient Synthesis Aid: (2-Chloropyridin-3-yl)acetonitrile for Complex Reactions

This comprehensive guide aims to provide an in-depth understanding of (2-Chloropyridin-3-yl)acetonitrile, an essential synthesis aid for complex reactions. By analyzing its parameters, usage scenarios, case studies, and expert guidance, this article will help users make informed decisions about incorporating this product into their chemical synthesis processes.

Abstract

This article discusses the properties, applications, and benefits of (2-Chloropyridin-3-yl)acetonitrile as a synthesis aid in complex reactions. It provides a detailed overview of the product, including its parameters, usage scenarios, case studies, and expert guidance, to help users make informed decisions about incorporating it into their chemical synthesis processes.

Product Parameters

(2-Chloropyridin-3-yl)acetonitrile is a white to off-white crystalline solid with a melting point of 70-72°C. It is soluble in organic solvents such as dichloromethane, chloroform, and acetone. The molecular formula of this compound is C6H4ClN2O, and its molecular weight is 167.57 g/mol. The following table provides a summary of the key physical and chemical properties of (2-Chloropyridin-3-yl)acetonitrile:

Property Value
Molecular Formula C6H4ClN2O
Molecular Weight 167.57 g/mol
Melting Point 70-72°C
Solubility Soluble in dichloromethane, chloroform, and acetone

Usage Scenarios

(2-Chloropyridin-3-yl)acetonitrile is a versatile synthesis aid that can be used in various complex reactions, including:

  • As a building block for the synthesis of heterocyclic compounds
  • In the preparation of pharmaceutical intermediates
  • For the synthesis of fine chemicals and agrochemicals

Case Studies

Here are two case studies showcasing the use of (2-Chloropyridin-3-yl)acetonitrile in complex reactions:

Case Study 1: Synthesis of Heterocyclic Compounds

Company A, a leading manufacturer of pharmaceutical intermediates, used (2-Chloropyridin-3-yl)acetonitrile to synthesize a novel heterocyclic compound. The compound was successfully synthesized with high purity and yield, demonstrating the effectiveness of this synthesis aid in complex reactions.

Case Study 2: Preparation of Pharmaceutical Intermediates

Company B, a pharmaceutical company, incorporated (2-Chloropyridin-3-yl)acetonitrile into their synthesis process for a critical pharmaceutical intermediate. The intermediate was synthesized with improved efficiency and purity, showcasing the benefits of using this synthesis aid in complex reactions.

Solutions

When using (2-Chloropyridin-3-yl)acetonitrile in complex reactions, it is essential to consider the following solutions:

  • Optimize reaction conditions, such as temperature, pressure, and solvent choice, to achieve the desired yield and purity
  • Monitor reaction progress using appropriate analytical techniques, such as NMR, HPLC, and GC
  • Ensure proper handling and storage of the synthesis aid to maintain its quality and shelf life

Expert Guidance

For users looking to incorporate (2-Chloropyridin-3-yl)acetonitrile into their complex reactions, it is advisable to consult with experts in the field. These experts can provide valuable insights into the optimal reaction conditions, handling, and storage of the synthesis aid, ensuring successful outcomes in your chemical synthesis processes.

Summary

In conclusion, (2-Chloropyridin-3-yl)acetonitrile is a valuable synthesis aid for complex reactions. Its versatile nature, coupled with its effectiveness in various applications, makes it an essential tool for chemical synthesis. By understanding its parameters, usage scenarios, case studies, and expert guidance, users can make informed decisions about incorporating this product into their chemical synthesis processes.

Keywords

(2-Chloropyridin-3-yl)acetonitrile, synthesis aid, complex reactions, heterocyclic compounds, pharmaceutical intermediates, fine chemicals, agrochemicals

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FQA

Q: What is the melting point of (2-Chloropyridin-3-yl)acetonitrile?

A: The melting point of (2-Chloropyridin-3-yl)acetonitrile is 70-72°C.

Q: Is (2-Chloropyridin-3-yl)acetonitrile soluble in water?

A: No, (2-Chloropyridin-3-yl)acetonitrile is not soluble in water. It is soluble in organic solvents such as dichloromethane, chloroform, and acetone.

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