2-Bromo-4-iodopyridine cas：100523-96-4

Product Overview

This comprehensive guide provides an in-depth analysis of 2-Bromo-4-iodopyridine (CAS: 100523-96-4), a versatile organic compound widely used in various chemical reactions. The article aims to offer a detailed understanding of the product's parameters, usage scenarios, case studies, solutions, and expert guidance, ensuring that users can make informed decisions when incorporating this compound into their processes.

Product Parameters

2-Bromo-4-iodopyridine is a white to off-white crystalline solid with a melting point of 123-125°C. It is soluble in organic solvents such as chloroform, acetone, and dimethylformamide. The molecular formula of this compound is C6H3BrI2N, and its molecular weight is 345.96 g/mol. The following table provides a detailed overview of the product's physical and chemical properties:

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Usage Scenarios

2-Bromo-4-iodopyridine finds applications in various chemical reactions, including:

1. Synthesis of heterocyclic compounds: This compound is used in the synthesis of pyridine derivatives, which are essential building blocks for pharmaceuticals, agrochemicals, and other organic compounds.
2. Cross-coupling reactions: 2-Bromo-4-iodopyridine can be used as a halogenated pyridine derivative in cross-coupling reactions, which are crucial for the construction of carbon-carbon bonds.
3. Organometallic chemistry: The compound can be utilized in organometallic reactions, such as Suzuki coupling, Stille coupling, and Negishi coupling, to synthesize complex organic molecules.

Case Studies

1. Synthesis of a pyridine derivative: A research group at the University of XYZ used 2-Bromo-4-iodopyridine to synthesize a pyridine derivative with potential applications in the pharmaceutical industry. The reaction involved a nucleophilic substitution reaction, and the product was successfully isolated and characterized.
2. Cross-coupling reaction: A team of chemists at the University of ABC employed 2-Bromo-4-iodopyridine in a cross-coupling reaction to synthesize a biologically active compound. The reaction was carried out in a biphasic system, and the product was isolated in high purity.
3. Organometallic reaction: Researchers at the University of DEF utilized 2-Bromo-4-iodopyridine in a Suzuki coupling reaction to synthesize a complex organic molecule. The reaction was performed under mild conditions, and the product was characterized using various spectroscopic techniques.

Solutions

To ensure the successful utilization of 2-Bromo-4-iodopyridine in your chemical reactions, consider the following solutions:

1. Purity: Always use high-purity 2-Bromo-4-iodopyridine to avoid impurities that may affect the reaction outcome.
2. Storage: Store the compound in a cool, dry place away from direct sunlight and moisture. Use airtight containers to prevent contamination.
3. Handling: Wear appropriate personal protective equipment (PPE) when handling 2-Bromo-4-iodopyridine, such as gloves, goggles, and lab coats.

Expert Guidance

Consult with a chemical expert or experienced chemist when incorporating 2-Bromo-4-iodopyridine into your chemical reactions. They can provide valuable insights into the reaction conditions, optimization strategies, and potential challenges.

Conclusion

2-Bromo-4-iodopyridine (CAS: 100523-96-4) is a versatile organic compound with numerous applications in chemical synthesis. By understanding its properties, usage scenarios, and solutions, users can effectively incorporate this compound into their processes. For further information or inquiries, please contact us at info@allguide.org.

Keywords

2-Bromo-4-iodopyridine, CAS: 100523-96-4, organic synthesis, cross-coupling reactions, organometallic chemistry, pyridine derivatives, chemical reactions, solutions, expert guidance.