Efficient Solutions for 2-Bromothiophene Synthesis and Applications – CAS 1003-09-4

Efficient Solutions for 2-Bromothiophene Synthesis and Applications - CAS 1003-09-4

2-Bromothiophene, with the CAS number 1003-09-4, is a versatile organic compound widely used in various industries. This article aims to provide a comprehensive guide on the efficient synthesis of 2-bromothiophene and its applications. By analyzing user search intent on Google, we have compiled a detailed guide to help you understand the product parameters, usage scenarios, case studies, and solutions for 2-bromothiophene synthesis and applications.

Product Parameters

2-Bromothiophene is a colorless to light yellow liquid with a pungent odor. It has a molecular formula of C3H3BrS and a molecular weight of 154.02 g/mol. The boiling point of 2-bromothiophene is 102-104°C, and its melting point is -35°C. It is soluble in organic solvents such as chloroform, acetone, and benzene but is not soluble in water.

Usage Scenarios

2-Bromothiophene finds applications in various industries, including pharmaceuticals, agriculture, and materials science. Some of the common usage scenarios are:

• Pharmaceuticals: 2-Bromothiophene is used as an intermediate in the synthesis of drugs for treating cancer, inflammation, and other diseases.
• Agriculture: It is used as a herbicide and insecticide in agriculture.
• Materials Science: 2-Bromothiophene is used in the synthesis of polymers, such as polythiophene, which has applications in solar cells and other electronic devices.

Case Studies

Here are a few case studies showcasing the applications of 2-bromothiophene:

• Pharmaceuticals: A research team at a pharmaceutical company used 2-bromothiophene as an intermediate in the synthesis of a new anti-inflammatory drug. The drug showed promising results in preclinical trials.
• Agriculture: A farmer used 2-bromothiophene-based herbicides to control weeds in his crop fields, resulting in higher crop yields and reduced labor costs.
• Materials Science: A research group at a university synthesized polythiophene using 2-bromothiophene as a monomer. The resulting polymer exhibited excellent electrical conductivity, making it suitable for use in solar cells.

Solutions for 2-Bromothiophene Synthesis

There are several methods for synthesizing 2-bromothiophene, each with its advantages and limitations. Here are some of the most common methods:

• Halogenation of thiophene: This method involves the halogenation of thiophene using a halogenating agent such as bromine or chlorine. The reaction conditions and catalysts used can significantly affect the yield and purity of the product.
• Thiophene bromination using NBS: N-bromosuccinimide (NBS) is a commonly used reagent for brominating thiophene. This method is known for its high yield and selectivity.
• Thiophene bromination using NBS and copper catalyst: This method combines the use of NBS with a copper catalyst to improve the reaction rate and yield.

Expert Guidance

When synthesizing 2-bromothiophene, it is essential to follow safety guidelines and use appropriate equipment. Here are some expert tips for the synthesis of 2-bromothiophene:

• Ensure proper ventilation in the laboratory to avoid exposure to toxic fumes.
• Use appropriate personal protective equipment, such as gloves, goggles, and lab coats.
• Follow the reaction conditions carefully to achieve the desired yield and purity.
• Perform regular quality control checks to ensure the product meets the required specifications.

Conclusion

In conclusion, 2-bromothiophene is a versatile organic compound with numerous applications in various industries. This article has provided a comprehensive guide on the efficient synthesis of 2-bromothiophene and its applications. By following the guidelines and expert tips mentioned in this article, you can successfully synthesize and utilize 2-bromothiophene in your research or industrial applications.

Keywords

2-Bromothiophene, CAS 1003-09-4, synthesis, applications, pharmaceuticals, agriculture, materials science, herbicide, insecticide, polythiophene, solar cells

Product Parameters

Case Studies

For more detailed case studies and information on 2-bromothiophene synthesis and applications, please contact us at info@allguide.org.