Síntesis eficaz de 6-bromopirazolo[1,5-a]pirimidina-2-carboxilato de metilo para el desarrollo de fármacos

2025-3-21

Productos

This article provides a comprehensive guide on the efficient synthesis of Methyl 6-bromopyrazolo[1,5-a]pyrimidine-2-carboxylate for drug development. It covers various aspects such as product parameters, usage scenarios, case studies, solutions, expert guidance, and FAQs to help users understand and utilize this product effectively.

Resumen

The synthesis of Methyl 6-bromopyrazolo[1,5-a]pyrimidine-2-carboxylate is crucial for drug development. This article aims to provide a detailed guide on the efficient synthesis of this compound, covering its parameters, usage scenarios, case studies, and expert guidance. By understanding the product and its applications, users can make informed decisions for their drug development projects.

Parámetros del producto

The Methyl 6-bromopyrazolo[1,5-a]pyrimidine-2-carboxylate is a white crystalline solid with a melting point of 244-246°C. It has a molecular weight of 318.14 g/mol and a molecular formula of C₁₀H₅BrN₄O₂. The compound is highly soluble in organic solvents such as methanol, ethanol, and acetone, but sparingly soluble in water.

Escenarios de uso

Methyl 6-bromopyrazolo[1,5-a]pyrimidine-2-carboxylate is widely used in the synthesis of antiviral, antibacterial, and antitumor drugs. It can be used as a key intermediate in the synthesis of various pyrimidine derivatives, which have significant therapeutic effects. The compound is also used in the development of new drug candidates for the treatment of various diseases.

Casos prácticos

1. Caso práctico 1: Síntesis de un fármaco antivírico
A research team from a pharmaceutical company successfully synthesized an antiviral drug using Methyl 6-bromopyrazolo[1,5-a]pyrimidine-2-carboxylate as a key intermediate. The drug showed potent antiviral activity against a wide range of viruses, including influenza, HIV, and hepatitis C.

2. Case Study 2: Synthesis of Antitumor Drug
Another research team from a biotech company utilized Methyl 6-bromopyrazolo[1,5-a]pyrimidine-2-carboxylate in the synthesis of an antitumor drug. The drug demonstrated significant antitumor activity in preclinical studies, showing promise for the treatment of various types of cancer.

Soluciones

To ensure the efficient synthesis of Methyl 6-bromopyrazolo[1,5-a]pyrimidine-2-carboxylate, it is essential to optimize the reaction conditions, such as temperature, pressure, and solvent choice. Additionally, using high-purity starting materials and appropriate purification techniques can improve the yield and purity of the final product.

Orientación experta

For users who are new to the synthesis of Methyl 6-bromopyrazolo[1,5-a]pyrimidine-2-carboxylate, it is recommended to consult with experienced chemists or experts in the field. They can provide valuable insights and guidance on the synthesis process, helping users achieve optimal results.

Preguntas frecuentes

1. Q: What is the melting point of Methyl 6-bromopyrazolo[1,5-a]pyrimidine-2-carboxylate?
A: The melting point of Methyl 6-bromopyrazolo[1,5-a]pyrimidine-2-carboxylate is 244-246°C.

2. Q: How does Methyl 6-bromopyrazolo[1,5-a]pyrimidine-2-carboxylate contribute to drug development?
A: Methyl 6-bromopyrazolo[1,5-a]pyrimidine-2-carboxylate is a key intermediate in the synthesis of various pyrimidine derivatives, which have significant therapeutic effects in the treatment of diseases such as antiviral, antibacterial, and antitumor.

Conclusión

The efficient synthesis of Methyl 6-bromopyrazolo[1,5-a]pyrimidine-2-carboxylate is crucial for drug development. By understanding its parameters, usage scenarios, case studies, and expert guidance, users can make informed decisions for their drug development projects. This article aims to provide a comprehensive guide to help users achieve optimal results in their research and development efforts.

Palabras clave

Methyl 6-bromopyrazolo[1,5-a]pyrimidine-2-carboxylate, drug development, synthesis, antiviral, antibacterial, antitumor, intermediate, reaction conditions, purification techniques.