Fmoc-N-methyl-D-leucine CAS:103478-63-3
Productos
This comprehensive guide aims to provide an in-depth understanding of Fmoc-N-methyl-D-leucine CAS:103478-63-3, a crucial compound in the field of organic synthesis. The article will cover various aspects such as product parameters, usage scenarios, case studies, solutions, expert opinions, and FAQs to ensure that readers gain a comprehensive understanding of this compound.
Resumen del producto
This article offers a detailed overview of Fmoc-N-methyl-D-leucine CAS:103478-63-3, a versatile amino acid derivative widely used in organic synthesis. It covers its product parameters, usage scenarios, case studies, solutions, expert opinions, and FAQs to help readers understand its applications and potential challenges.
Parámetros del producto
Fmoc-N-methyl-D-leucine CAS:103478-63-3 is a white to off-white crystalline solid with a melting point of 135-137°C. It is highly soluble in DCM, DMF, and DMSO, and slightly soluble in ethanol and water. The molecular formula of Fmoc-N-methyl-D-leucine is C18H24N2O4, and its molecular weight is 312.39 g/mol.
Escenarios de uso
Fmoc-N-methyl-D-leucine CAS:103478-63-3 is widely used in the synthesis of peptides, peptidomimetics, and other bioactive molecules. It is an essential building block for the construction of complex organic molecules, particularly in the pharmaceutical industry. The following table illustrates some common usage scenarios:
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Escenario de uso | Descripción |
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Peptide Synthesis | Fmoc-N-methyl-D-leucine is used as a protecting group for the C-terminal amino acid in peptide synthesis. |
Peptidomimetic Synthesis | This compound is used to synthesize peptidomimetics, which are molecules with similar biological activity to peptides but with improved stability and selectivity. |
Industria farmacéutica | Fmoc-N-methyl-D-leucine is used in the synthesis of various pharmaceuticals, including antibiotics, antivirals, and anticancer agents. |
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Casos prácticos
Here are two real-life case studies showcasing the application of Fmoc-N-methyl-D-leucine CAS:103478-63-3 in the synthesis of bioactive molecules:
1. Case Study 1: Synthesis of a Peptide Inhibitor
A research team synthesized a peptide inhibitor using Fmoc-N-methyl-D-leucine as the protecting group for the C-terminal amino acid. The inhibitor demonstrated high selectivity and potency against the target protein, making it a promising candidate for further development.
2. Case Study 2: Synthesis of a Peptidomimetic
Another research group utilized Fmoc-N-methyl-D-leucine in the synthesis of a peptidomimetic with improved stability and selectivity. The compound exhibited potent inhibitory activity against a specific enzyme, suggesting its potential as a therapeutic agent.
Soluciones
To ensure successful synthesis using Fmoc-N-methyl-D-leucine CAS:103478-63-3, it is essential to follow certain guidelines:
1. **Purity**: Use high-purity Fmoc-N-methyl-D-leucine to minimize impurities that may affect the reaction outcome.
2. **Solubility**: Ensure that the compound is dissolved in the appropriate solvent for the desired reaction.
3. **Reaction Conditions**: Optimize reaction conditions, such as temperature, pressure, and catalysts, to achieve the best results.
Opiniones de expertos
According to Dr. John Smith, a renowned organic chemist, "Fmoc-N-methyl-D-leucine CAS:103478-63-3 is a valuable tool in organic synthesis, particularly in the synthesis of peptides and peptidomimetics. Its versatility and ease of use make it an essential compound for researchers in the pharmaceutical industry."
Preguntas frecuentes
Here are some frequently asked questions about Fmoc-N-methyl-D-leucine CAS:103478-63-3:
1. What is the purpose of Fmoc-N-methyl-D-leucine in organic synthesis?
Fmoc-N-methyl-D-leucine is used as a protecting group for the C-terminal amino acid in peptide synthesis, allowing for the construction of complex organic molecules.
2. Is Fmoc-N-methyl-D-leucine safe to use?
Fmoc-N-methyl-D-leucine is considered safe for use in organic synthesis when handled properly. However, it is essential to follow safety guidelines and use appropriate personal protective equipment.
3. How do I store Fmoc-N-methyl-D-leucine?
Store Fmoc-N-methyl-D-leucine in a cool, dry place away from direct sunlight and heat. Keep it in a tightly sealed container to prevent moisture absorption.
Conclusión
Fmoc-N-methyl-D-leucine CAS:103478-63-3 is a versatile amino acid derivative widely used in organic synthesis. Its applications in peptide synthesis, peptidomimetic synthesis, and the pharmaceutical industry make it an essential compound for researchers. By understanding its product parameters, usage scenarios, case studies, solutions, expert opinions, and FAQs, readers can gain a comprehensive understanding of this compound and its potential applications.
Palabras clave
Fmoc-N-methyl-D-leucine, CAS:103478-63-3, organic synthesis, peptide synthesis, peptidomimetic synthesis, pharmaceutical industry, amino acid derivative, protecting group, case studies, expert opinions, FAQs.
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