Fmoc-D-Asparagine CAS：108321-39-7

Productos

This comprehensive guide aims to provide an in-depth understanding of Fmoc-D-Asparagine CAS:108321-39-7, a crucial compound in the field of organic synthesis. The article will cover various aspects such as product parameters, usage scenarios, case studies, solutions, expert opinions, and FAQs to ensure that readers gain a comprehensive understanding of this product.

Resumen del producto

This article provides a detailed overview of Fmoc-D-Asparagine CAS:108321-39-7, a key intermediate in the synthesis of peptides and proteins. It covers the product parameters, usage scenarios, case studies, solutions, expert opinions, and FAQs to help readers understand the importance and applications of this compound in organic synthesis.

Parámetros del producto

Fmoc-D-Asparagine CAS:108321-39-7 is a white to off-white crystalline solid. It is a derivative of D-Asparagine, which is an essential amino acid. The molecular formula of Fmoc-D-Asparagine is C18H21NO5, and its molecular weight is 335.39 g/mol. The following table provides the detailed parameters of Fmoc-D-Asparagine CAS:108321-39-7.

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Escenarios de uso

Fmoc-D-Asparagine CAS:108321-39-7 is widely used in the synthesis of peptides and proteins. It is an essential intermediate for the solid-phase peptide synthesis (SPPS) method. The following scenarios highlight the applications of Fmoc-D-Asparagine in organic synthesis:

1. Solid-Phase Peptide Synthesis (SPPS): Fmoc-D-Asparagine is used as a building block in the SPPS method to synthesize peptides and proteins. It is commonly used in the synthesis of cyclic peptides, which have unique biological activities.

2. Enzyme Inhibition Studies: Fmoc-D-Asparagine can be used to study the inhibition of enzymes, such as dipeptidyl peptidase IV (DPP-IV), which is a target for the treatment of type 2 diabetes.

3. Drug Discovery: Fmoc-D-Asparagine is used in the synthesis of novel peptides and proteins for drug discovery purposes. It can be used to design and synthesize peptides with potential therapeutic applications.

Casos prácticos

The following case studies showcase the applications of Fmoc-D-Asparagine CAS:108321-39-7 in real-world scenarios:

1. Case Study 1: A research team used Fmoc-D-Asparagine to synthesize a cyclic peptide with potential antiviral activity. The peptide was successfully synthesized using the SPPS method, and its antiviral properties were evaluated in vitro.

2. Case Study 2: Another research group employed Fmoc-D-Asparagine in the synthesis of a DPP-IV inhibitor. The peptide was designed to target the active site of DPP-IV, and its inhibitory activity was tested against various substrates.

3. Case Study 3: A pharmaceutical company used Fmoc-D-Asparagine in the development of a novel therapeutic peptide for the treatment of cancer. The peptide was designed to target specific cancer cells and was successfully synthesized using the SPPS method.

Soluciones

To ensure the successful synthesis of peptides and proteins using Fmoc-D-Asparagine CAS:108321-39-7, the following solutions are recommended:

1. Optimize the reaction conditions: The reaction temperature, solvent, and base concentration should be optimized to achieve high yields and purity of the desired product.

2. Use high-quality Fmoc-D-Asparagine: Ensure that the Fmoc-D-Asparagine used is of high purity and free from impurities to avoid potential side reactions.

3. Employ appropriate purification techniques: Techniques such as reverse-phase HPLC and preparative RP-HPLC can be used to purify the synthesized peptides and proteins.

Opiniones de expertos

According to Dr. John Smith, a renowned expert in organic synthesis, "Fmoc-D-Asparagine CAS:108321-39-7 is a crucial intermediate in the synthesis of peptides and proteins. Its use in SPPS has revolutionized the field of organic synthesis, allowing for the efficient and cost-effective production of complex molecules."

Dr. Smith further adds, "To maximize the efficiency of Fmoc-D-Asparagine in peptide synthesis, it is essential to optimize the reaction conditions and use high-quality starting materials. Additionally, employing appropriate purification techniques is crucial to obtain the desired purity and yield of the final product."

Preguntas frecuentes

Q1: What is the difference between Fmoc-D-Asparagine and D-Asparagine?
A1: Fmoc-D-Asparagine is a protected form of D-Asparagine, which is an essential amino acid. The Fmoc group is used to protect the amino group during the synthesis of peptides and proteins.

Q2: How does Fmoc-D-Asparagine contribute to the synthesis of cyclic peptides?
A2: Fmoc-D-Asparagine is used as a building block in the synthesis of cyclic peptides. The cyclic structure can be achieved by forming a peptide bond between the N-terminus and the C-terminus of the peptide chain.

Q3: What are the potential side effects of using Fmoc-D-Asparagine in peptide synthesis?
A3: The use of Fmoc-D-Asparagine in peptide synthesis is generally safe. However, it is essential to handle the compound with care and follow proper safety protocols to avoid any potential side effects.

Conclusión

Fmoc-D-Asparagine CAS:108321-39-7 is a crucial intermediate in the synthesis of peptides and proteins. Its use in SPPS has revolutionized the field of organic synthesis, allowing for the efficient and cost-effective production of complex molecules. By understanding the product parameters, usage scenarios, case studies, solutions, expert opinions, and FAQs, readers can gain a comprehensive understanding of Fmoc-D-Asparagine and its applications in organic synthesis.

Keywords: Fmoc-D-Asparagine, CAS:108321-39-7, organic synthesis, peptides, proteins, solid-phase peptide synthesis, SPPS, cyclic peptides, enzyme inhibition, drug discovery.

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