Lithium tri-tert-butoxyaluminum hydride CAS：17476-04-9

2025-3-23

Productos

This comprehensive guide provides an in-depth analysis of Lithium tri-tert-butoxyaluminum hydride (CAS: 17476-04-9), a crucial reagent in organic synthesis. The article aims to offer a detailed understanding of the product's parameters, usage scenarios, case studies, solutions, expert advice, and FAQs, catering to the needs of users seeking reliable information.

Resumen del producto

Lithium tri-tert-butoxyaluminum hydride (CAS: 17476-04-9) is a versatile reagent widely used in organic synthesis for the formation of carbon-hydrogen bonds. This guide will explore the product's key features, applications, and benefits, providing users with a comprehensive understanding of its usage and potential solutions.

Parámetros del producto

The following table provides a detailed overview of the key parameters of Lithium tri-tert-butoxyaluminum hydride (CAS: 17476-04-9):

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Parámetro	Valor
Apariencia	Aceite incoloro a amarillo pálido
Punto de ebullición	70-72°C
Punto de fusión	-60°C
Punto de inflamación	10°C
Temperatura de almacenamiento	-20°C to -30°C

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Escenarios de uso

Lithium tri-tert-butoxyaluminum hydride (CAS: 17476-04-9) is a versatile reagent used in various organic synthesis reactions. Some common usage scenarios include:

1. Formation of carbon-hydrogen bonds: Lithium tri-tert-butoxyaluminum hydride is widely used for the formation of carbon-hydrogen bonds in organic synthesis. This reagent is particularly effective in the reduction of aldehydes, ketones, and esters to alcohols.
2. Synthesis of alkenes: The reagent can be used in the synthesis of alkenes through the dehydrohalogenation of alkyl halides.
3. Synthesis of heterocycles: Lithium tri-tert-butoxyaluminum hydride is also used in the synthesis of heterocycles, such as pyrroles, indoles, and imidazoles.

Casos prácticos

The following case studies showcase the application of Lithium tri-tert-butoxyaluminum hydride (CAS: 17476-04-9) in real-world scenarios:

1. Synthesis of a pharmaceutical intermediate: A pharmaceutical company used Lithium tri-tert-butoxyaluminum hydride to synthesize a key intermediate for a new drug. The reagent facilitated the reduction of an aldehyde to an alcohol, which was then used in the subsequent steps of the synthesis.
2. Synthesis of a natural product: A research group employed Lithium tri-tert-butoxyaluminum hydride in the synthesis of a natural product. The reagent was used to reduce a ketone to an alcohol, which was crucial for the formation of the desired structure.
3. Synthesis of a fine chemical: A chemical company utilized Lithium tri-tert-butoxyaluminum hydride in the synthesis of a fine chemical. The reagent was used to reduce an ester to an alcohol, which was then further processed to obtain the final product.

Soluciones

To ensure the successful application of Lithium tri-tert-butoxyaluminum hydride (CAS: 17476-04-9), it is essential to consider the following solutions:

1. Proper handling and storage: Store the reagent in a cool, dry place, away from direct sunlight and sources of ignition. Use appropriate safety equipment, such as gloves and goggles, when handling the reagent.
2. Reaction optimization: Optimize the reaction conditions, such as temperature, pressure, and solvent choice, to achieve the desired yield and purity of the product.
3. Alternative reagents: In some cases, alternative reagents may be more suitable for specific reactions. Consider exploring alternative reagents based on the specific requirements of your synthesis.

Consejos de expertos

Based on our extensive research and experience, we offer the following expert advice for the usage of Lithium tri-tert-butoxyaluminum hydride (CAS: 17476-04-9):

1. Always use the reagent in a well-ventilated area to avoid exposure to harmful fumes.
2. Be cautious when handling the reagent, as it may react with water and release hydrogen gas.
3. Keep the reagent away from incompatible materials, such as oxidizing agents and strong acids.

Preguntas frecuentes

Here are some frequently asked questions about Lithium tri-tert-butoxyaluminum hydride (CAS: 17476-04-9):

1. Q: What is the shelf life of Lithium tri-tert-butoxyaluminum hydride?
A: The shelf life of the reagent is typically 2 years when stored under appropriate conditions.
2. Q: Can Lithium tri-tert-butoxyaluminum hydride be used in the synthesis of polymers?
A: Yes, the reagent can be used in the synthesis of certain polymers, such as polyethylene.
3. Q: Is Lithium tri-tert-butoxyaluminum hydride compatible with all solvents?
A: No, the reagent is not compatible with all solvents. It is essential to consult the manufacturer's guidelines for the appropriate solvent choice.

Conclusión

Lithium tri-tert-butoxyaluminum hydride (CAS: 17476-04-9) is a versatile reagent widely used in organic synthesis. This guide has provided a comprehensive overview of the product's parameters, usage scenarios, case studies, solutions, expert advice, and FAQs. By following the guidelines and recommendations outlined in this article, users can ensure the successful application of this reagent in their organic synthesis processes.

Palabras clave

Lithium tri-tert-butoxyaluminum hydride, CAS: 17476-04-9, organic synthesis, carbon-hydrogen bond formation, aldehyde reduction, ketone reduction, ester reduction, heterocycle synthesis, pharmaceutical intermediate, natural product synthesis, fine chemical synthesis, expert advice, FAQs.