Efficient Solvent for Chemical Synthesis： Cyclohexanone CAS 108-94-1 – Solve Your Reaction Needs

2025-3-21

Efficient Solvent for Chemical Synthesis: Cyclohexanone CAS 108-94-1 - Solve Your Reaction Needs

Chemical synthesis is a critical process in the pharmaceutical, agrochemical, and fine chemical industries. The choice of solvent plays a pivotal role in the efficiency and success of these reactions. This guide focuses on cyclohexanone, a versatile solvent with CAS number 108-94-1, offering solutions to various reaction needs.

Resumen

This article provides an in-depth analysis of cyclohexanone, a highly efficient solvent for chemical synthesis. It covers product parameters, usage scenarios, case studies, solutions, expert guidance, and FAQs to help users make informed decisions. By understanding the benefits and applications of cyclohexanone, chemists can optimize their reaction processes and achieve desired results.

Parámetros del producto

Cyclohexanone, with the chemical formula C6H10O, is a colorless liquid with a characteristic odor. It has a boiling point of 156.2°C and a melting point of -47.7°C. The molecular weight of cyclohexanone is 98.15 g/mol. It is a polar solvent with a dielectric constant of 6.8 at 25°C.

Escenarios de uso

Cyclohexanone is widely used in various chemical reactions due to its unique properties. Some common usage scenarios include:

As a solvent in organic synthesis, particularly for reactions involving aldehydes, ketones, and carboxylic acids.
In the production of pharmaceuticals, agrochemicals, and fine chemicals.
As a solvent for extraction and purification processes.

Casos prácticos

Here are two case studies showcasing the use of cyclohexanone in chemical synthesis:

Case Study 1: Synthesis of Ibuprofen

In the synthesis of ibuprofen, cyclohexanone is used as a solvent for the reaction between 2-phenylpropionic acid and isobutyl alcohol. The reaction is carried out at 60°C for 4 hours. The resulting product is then purified using cyclohexanone as the eluent in a column chromatography.

Case Study 2: Production of Ethyl Acetate

Ethyl acetate is produced by the esterification of acetic acid and ethanol in the presence of a catalyst. Cyclohexanone is used as a solvent for the reaction mixture, which is heated at 80°C for 2 hours. The product is then extracted using cyclohexanone and purified through distillation.

Soluciones

Cyclohexanone offers several advantages as a solvent for chemical synthesis:

High solubility for a wide range of organic compounds.
Low toxicity and environmental impact.
Excellent thermal stability and volatility.

Orientación experta

When using cyclohexanone as a solvent, it is essential to follow safety guidelines and best practices:

Handle cyclohexanone with care, wearing appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats.
Ensure proper ventilation in the laboratory to avoid exposure to vapors.
Store cyclohexanone in a cool, dry place away from direct sunlight and incompatible materials.

Preguntas frecuentes

Here are some frequently asked questions about cyclohexanone:

Q: Is cyclohexanone flammable?
A: Yes, cyclohexanone is flammable. It should be handled and stored in accordance with fire safety regulations.
Q: Can cyclohexanone be recycled?
A: Yes, cyclohexanone can be recycled through distillation and purification processes.
Q: What are the health hazards of cyclohexanone?
A: Cyclohexanone can cause irritation to the eyes, skin, and respiratory system. Long-term exposure may lead to liver and kidney damage.

Conclusión

Cyclohexanone is a highly efficient solvent for chemical synthesis, offering numerous benefits for various reactions. By understanding its properties, usage scenarios, and safety guidelines, chemists can optimize their reaction processes and achieve desired results. This guide provides a comprehensive overview of cyclohexanone, helping users make informed decisions for their chemical synthesis needs.

Palabras clave

Cyclohexanone, CAS 108-94-1, solvent, chemical synthesis, organic synthesis, pharmaceuticals, agrochemicals, fine chemicals, reaction needs, safety guidelines