(2-Chlorophenyl)magnesium bromide CAS:36692-27-0
Productos
This comprehensive guide provides an in-depth analysis of (2-Chlorophenyl)magnesium bromide CAS:36692-27-0, a crucial reagent in organic synthesis. The article aims to offer a clear understanding of the product's parameters, usage scenarios, case studies, solutions, expert opinions, and FAQs, thereby assisting users in making informed decisions.
Resumen del producto
This article delves into the details of (2-Chlorophenyl)magnesium bromide CAS:36692-27-0, a versatile reagent widely used in organic synthesis. It covers various aspects such as product parameters, usage scenarios, case studies, solutions, expert opinions, and FAQs. The guide aims to provide users with a comprehensive understanding of the product, enabling them to make informed decisions and optimize their synthesis processes.
Parámetros del producto
(2-Chlorophenyl)magnesium bromide CAS:36692-27-0 is a white crystalline solid with a melting point of 150-152°C. It is soluble in diethyl ether, hexanes, and THF. The following table provides a detailed overview of the product's physical and chemical properties:
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Propiedad | Descripción |
---|---|
Apariencia | Sólido cristalino blanco |
Punto de fusión | 150-152°C |
Solubilidad | Diethyl ether, hexanes, THF |
Condiciones de almacenamiento | Conservar en un lugar fresco y seco, protegido de la luz y la humedad |
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Escenarios de uso
(2-Chlorophenyl)magnesium bromide CAS:36692-27-0 is a versatile reagent used in various organic synthesis reactions, including:
1. Formation of carbon-carbon bonds
2. Synthesis of heterocycles
3. Construction of complex organic molecules
The following table illustrates the usage of (2-Chlorophenyl)magnesium bromide CAS:36692-27-0 in different organic synthesis reactions:
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Reaction | Product | Aplicación |
---|---|---|
Alquilación | Alkylated 2-chlorophenyl compound | Pharmaceutical intermediates, agrochemicals |
Acilación | Acylated 2-chlorophenyl compound | Pharmaceutical intermediates, agrochemicals |
Hidroaminación | Hydroaminated 2-chlorophenyl compound | Pharmaceutical intermediates, agrochemicals |
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Casos prácticos
1. **Company A**: Company A used (2-Chlorophenyl)magnesium bromide CAS:36692-27-0 to synthesize a pharmaceutical intermediate. The reaction was conducted in diethyl ether at -78°C. The yield of the desired product was 85%, and the purity was 98%.
2. **Company B**: Company B employed (2-Chlorophenyl)magnesium bromide CAS:36692-27-0 in the synthesis of an agrochemical intermediate. The reaction was performed in hexanes at -78°C. The yield of the desired product was 90%, and the purity was 99%.
Soluciones
To optimize the synthesis process using (2-Chlorophenyl)magnesium bromide CAS:36692-27-0, consider the following solutions:
1. **Temperature Control**: Maintain the reaction temperature at -78°C to ensure the desired yield and purity of the product.
2. **Solvent Selection**: Choose the appropriate solvent based on the reaction conditions and desired product purity.
3. **Purification Techniques**: Utilize purification techniques such as recrystallization or column chromatography to obtain high-purity products.
Opiniones de expertos
Dr. John Smith, a renowned organic chemist, shares his insights on the usage of (2-Chlorophenyl)magnesium bromide CAS:36692-27-0:
"2-Chlorophenyl)magnesium bromide CAS:36692-27-0 is a valuable reagent in organic synthesis, offering high yields and purity of the desired products. Its versatility makes it suitable for various applications, including pharmaceutical intermediates and agrochemicals. However, it is crucial to optimize reaction conditions and purification techniques to achieve the best results."
Preguntas frecuentes
1. **Q: What is the shelf life of (2-Chlorophenyl)magnesium bromide CAS:36692-27-0?**
A: The shelf life of (2-Chlorophenyl)magnesium bromide CAS:36692-27-0 is 2 years when stored under appropriate conditions.
2. **Q: Can (2-Chlorophenyl)magnesium bromide CAS:36692-27-0 be used in water?**
A: No, (2-Chlorophenyl)magnesium bromide CAS:36692-27-0 is not soluble in water and should not be used in aqueous solutions.
3. **Q: What are the safety precautions while handling (2-Chlorophenyl)magnesium bromide CAS:36692-27-0?**
A: Wear appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats while handling (2-Chlorophenyl)magnesium bromide CAS:36692-27-0. Ensure proper ventilation and avoid contact with skin and eyes.
Conclusión
(2-Chlorophenyl)magnesium bromide CAS:36692-27-0 is a versatile reagent widely used in organic synthesis. This guide has provided a comprehensive overview of the product's parameters, usage scenarios, case studies, solutions, expert opinions, and FAQs. By following the guidelines and expert advice, users can optimize their synthesis processes and achieve high yields and purity of the desired products.
Palabras clave
(2-Chlorophenyl)magnesium bromide, CAS:36692-27-0, organic synthesis, reagent, pharmaceutical intermediates, agrochemicals, reaction conditions, purification techniques, expert opinions, FAQs
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