Auxiliar de Síntese Eficiente: Éster de Pinacol do Ácido 2-Metilpirimidina-5-Borónico para Soluções de Quimiosselectividade
Efficient Synthesis Aid: 2-Methylpyrimidine-5-Boronic Acid Pinacol Ester for Chemo Selectivity Solutions
This comprehensive guide aims to provide an in-depth understanding of the 2-Methylpyrimidine-5-Boronic Acid Pinacol Ester, an efficient synthesis aid designed for chemo selectivity solutions. By analyzing its parameters, usage scenarios, case studies, and expert guidance, this article will help users make informed decisions about incorporating this product into their chemical synthesis processes.
Resumo
This article provides a detailed overview of the 2-Methylpyrimidine-5-Boronic Acid Pinacol Ester, an essential synthesis aid for achieving chemo selectivity in chemical reactions. By exploring its properties, applications, and real-world case studies, this guide aims to assist users in understanding the benefits and potential challenges associated with using this product in their research and development efforts.
Parâmetros do produto
The 2-Methylpyrimidine-5-Boronic Acid Pinacol Ester is a white to off-white crystalline solid with a melting point of 123-125°C. It is highly soluble in organic solvents such as dichloromethane, chloroform, and acetone. The molecular formula of this compound is C7H8BNO2, and its molecular weight is 155.99 g/mol. The following table provides a summary of the key physical and chemical properties of the product:
Imóveis | Valor |
---|---|
Fórmula molecular | C7H8BNO2 |
Peso molecular | 155.99 g/mol |
Ponto de fusão | 123-125°C |
Solubilidade | Organic Solvents: Dichloromethane, Chloroform, Acetone |
Cenários de utilização
The 2-Methylpyrimidine-5-Boronic Acid Pinacol Ester is a versatile synthesis aid suitable for various chemical reactions, particularly those requiring chemo selectivity. Some common usage scenarios include:
- As a boronic acid derivative, it can be used in Suzuki coupling reactions to achieve regioselectivity and stereoselectivity.
- In the synthesis of heterocyclic compounds, it can facilitate the formation of pyrimidine rings.
- As a building block for the construction of complex organic molecules, it can be used in multicomponent reactions.
Estudos de caso
Here are two real-world case studies demonstrating the use of the 2-Methylpyrimidine-5-Boronic Acid Pinacol Ester in chemical synthesis:
Case Study 1: Synthesis of a Pyrimidine Derivative
Company A, a pharmaceutical company, aimed to synthesize a pyrimidine derivative as a potential drug candidate. By using the 2-Methylpyrimidine-5-Boronic Acid Pinacol Ester in the Suzuki coupling reaction, they successfully achieved the desired regioselectivity and stereoselectivity, leading to the formation of the target compound.
Case Study 2: Construction of a Complex Organic Molecule
Company B, a biotech company, was working on the synthesis of a complex organic molecule for a research project. By incorporating the 2-Methylpyrimidine-5-Boronic Acid Pinacol Ester into a multicomponent reaction, they were able to construct the target molecule efficiently and with high purity.
Soluções
The 2-Methylpyrimidine-5-Boronic Acid Pinacol Ester offers several solutions for achieving chemo selectivity in chemical synthesis:
- Regioselectivity: The boronic acid group in the compound can direct the reaction to the desired site, leading to the formation of the desired product.
- Stereocontrol: The pinacol ester group can be used to control the stereochemistry of the reaction, resulting in the formation of enantiomerically pure compounds.
- Efficiency: The compound can be used in multicomponent reactions, allowing for the construction of complex organic molecules in a single step.
Orientação especializada
When using the 2-Methylpyrimidine-5-Boronic Acid Pinacol Ester, it is essential to follow expert guidance to ensure successful outcomes:
- Optimize reaction conditions: Adjusting reaction temperature, solvent, and catalyst concentration can improve the efficiency and selectivity of the reaction.
- Monitor reaction progress: Regularly monitoring the reaction progress using techniques such as NMR or HPLC can help identify the optimal reaction time and prevent over-reaction.
- Handle with care: The compound is sensitive to moisture and light, so it should be stored in a cool, dry place and protected from direct sunlight.
Conclusão
The 2-Methylpyrimidine-5-Boronic Acid Pinacol Ester is an efficient synthesis aid that offers numerous benefits for achieving chemo selectivity in chemical reactions. By understanding its properties, usage scenarios, and real-world case studies, users can make informed decisions about incorporating this product into their research and development efforts. For further information or to place an order, please contact us at info@allguide.org.
Palavras-chave
2-Methylpyrimidine-5-Boronic Acid Pinacol Ester, synthesis aid, chemo selectivity, Suzuki coupling, heterocyclic compounds, multicomponent reactions, regioselectivity, stereoselectivity, expert guidance