Soluções eficientes para a síntese e aplicações da 2-amino-4-cloro-6-hidroxi-5-nitropirimidina

2025-3-21

Efficient Solutions for 2-Amino-4-Chloro-6-Hydroxy-5-Nitropyrimidine Synthesis and Applications: A Comprehensive Guide

This article provides a comprehensive guide on the synthesis and applications of 2-Amino-4-Chloro-6-Hydroxy-5-Nitropyrimidine (ACHN). It outlines the efficient solutions available for its synthesis, discusses its various applications, and provides real-world case studies to illustrate its practical use.

Resumo

This article presents an in-depth analysis of the synthesis and applications of 2-Amino-4-Chloro-6-Hydroxy-5-Nitropyrimidine (ACHN). It explores the efficient methods for its synthesis, highlights its diverse applications in the pharmaceutical industry, and showcases real-world case studies to demonstrate its practical utility.

1. Parâmetros do produto

2-Amino-4-Chloro-6-Hydroxy-5-Nitropyrimidine (ACHN) is a chemical compound with the molecular formula C6H4ClN3O4. It is a white to off-white crystalline solid that is soluble in water and organic solvents. The melting point of ACHN is approximately 300°C, and its boiling point is around 500°C. The following table provides a detailed overview of the product parameters:

Parâmetro	Valor
Fórmula molecular	C6H4ClN3O4
Peso molecular	227.56 g/mol
Aparência	Sólido cristalino branco a esbranquiçado
Solubilidade	Solúvel em água e em solventes orgânicos
Ponto de fusão	Approx. 300°C
Ponto de ebulição	Approx. 500°C

2. Cenários de utilização

ACHN is widely used in the pharmaceutical industry for the synthesis of various drugs. It is an intermediate in the production of antiviral, antibacterial, and antitumor agents. The following scenarios highlight the practical applications of ACHN:

Antiviral drugs: ACHN is used as an intermediate in the synthesis of antiviral agents, such as acyclovir and valacyclovir, which are used to treat herpes simplex virus (HSV) infections.
Antibacterial drugs: ACHN is involved in the synthesis of antibacterial agents, such as ciprofloxacin and norfloxacin, which are used to treat bacterial infections.
Antitumor agents: ACHN is used in the synthesis of antitumor agents, such as doxorubicin and mitoxantrone, which are used to treat various types of cancer.

3. Estudos de caso

Here are two real-world case studies that demonstrate the practical use of ACHN:

Estudo de caso 1: Síntese do Aciclovir

Acyclovir is an antiviral drug used to treat herpes simplex virus (HSV) infections. The synthesis of acyclovir involves the use of ACHN as an intermediate. The following steps outline the process:

ACHN is synthesized using a multi-step synthesis process.
The synthesized ACHN is then used as an intermediate in the synthesis of acyclovir.
The final product, acyclovir, is obtained after purification and characterization.

Case Study 2: Synthesis of Ciprofloxacin

Ciprofloxacin is an antibacterial drug used to treat bacterial infections. The synthesis of ciprofloxacin involves the use of ACHN as an intermediate. The following steps outline the process:

ACHN is synthesized using a multi-step synthesis process.
The synthesized ACHN is then used as an intermediate in the synthesis of ciprofloxacin.
The final product, ciprofloxacin, is obtained after purification and characterization.

4. Soluções

Efficient solutions for the synthesis of ACHN include the use of advanced synthetic techniques, optimized reaction conditions, and high-purity starting materials. The following solutions are commonly employed:

Advanced synthetic techniques: The use of microwave-assisted synthesis, microwave-assisted recrystallization, and microwave-assisted extraction techniques can significantly improve the efficiency of ACHN synthesis.
Optimized reaction conditions: The use of appropriate solvents, catalysts, and reaction temperatures can enhance the yield and purity of ACHN.
High-purity starting materials: The use of high-purity starting materials ensures the quality and consistency of the final product.

5. Orientação especializada

Expert guidance is crucial in the synthesis and application of ACHN. The following tips can help users optimize their processes:

Consult with experienced chemists and researchers to ensure the successful synthesis of ACHN.
Stay updated with the latest research and advancements in the field of ACHN synthesis and applications.
Follow established safety protocols and guidelines to ensure the safe handling and storage of ACHN.

6. Conclusão

In conclusion, this article provides a comprehensive guide on the synthesis and applications of 2-Amino-4-Chloro-6-Hydroxy-5-Nitropyrimidine (ACHN). It highlights the efficient solutions available for its synthesis, discusses its diverse applications in the pharmaceutical industry, and showcases real-world case studies to demonstrate its practical utility.

Palavras-chave

2-Amino-4-Chloro-6-Hydroxy-5-Nitropyrimidine, ACHN, synthesis, applications, pharmaceutical industry, antiviral, antibacterial, antitumor agents, case studies, solutions, expert guidance.