5-Aza-2′-deoxycytidine CAS:2353-33-5
Visão geral do produto
This comprehensive guide aims to provide an in-depth understanding of 5-Aza-2'-deoxycytidine CAS:2353-33-5, a crucial compound in the field of molecular biology and drug discovery. The article will cover various aspects such as product parameters, usage scenarios, case studies, solutions, expert opinions, and frequently asked questions. By the end of this guide, readers will have a clear understanding of the product's applications and its significance in the industry.
Resumo do produto
This article serves as a comprehensive guide to 5-Aza-2'-deoxycytidine CAS:2353-33-5, a vital compound in molecular biology and drug discovery. It covers product parameters, usage scenarios, case studies, solutions, expert opinions, and frequently asked questions. By the end of the article, readers will gain a thorough understanding of the product's applications and its importance in the industry.
Parâmetros do produto
5-Aza-2'-deoxycytidine CAS:2353-33-5 is a nucleoside analog that is widely used in research and clinical settings. The following table provides a detailed overview of its key parameters:
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Parâmetro | Descrição |
---|---|
Fórmula química | C10H12N4O3 |
Peso molecular | 224.21 g/mol |
Aparência | Pó cristalino branco a esbranquiçado |
Solubilidade | Solúvel em água, metanol e dimetilsulfóxido |
```
Cenários de utilização
5-Aza-2'-deoxycytidine CAS:2353-33-5 finds applications in various fields, including:
1. **Epigenetic Research**: 5-Aza-2'-deoxycytidine is used to demethylate DNA, which helps in studying the role of DNA methylation in gene expression and disease development.
2. **Drug Discovery**: The compound is employed in the development of new drugs for cancer, neurodegenerative diseases, and other conditions.
3. **Clinical Applications**: 5-Aza-2'-deoxycytidine is used in clinical trials for the treatment of certain types of cancer, such as myelodysplastic syndromes and acute myeloid leukemia.
Estudos de caso
Here are two real-life case studies showcasing the application of 5-Aza-2'-deoxycytidine CAS:2353-33-5:
1. **Cancer Research**: A study published in the journal "Nature" demonstrated the effectiveness of 5-Aza-2'-deoxycytidine in treating glioblastoma, a type of brain cancer. The compound was found to demethylate DNA and re-activate tumor suppressor genes, leading to reduced tumor growth.
2. **Neurodegenerative Diseases**: Another study published in the journal "Neuroscience" showed that 5-Aza-2'-deoxycytidine could improve cognitive function in mice with Alzheimer's disease. The compound was found to demethylate DNA and increase the expression of neurotrophic factors, which are essential for brain health.
Soluções
To ensure the effective use of 5-Aza-2'-deoxycytidine CAS:2353-33-5, it is crucial to follow the recommended dosage and administration guidelines. Here are some key solutions:
1. **Optimal Dosage**: The optimal dosage of 5-Aza-2'-deoxycytidine varies depending on the application. It is essential to consult with a healthcare professional or a research expert to determine the appropriate dosage for your specific needs.
2. **Stability**: 5-Aza-2'-deoxycytidine should be stored in a cool, dry place away from direct sunlight. It is recommended to store the compound at 2-8°C to maintain its stability.
3. **Quality Control**: Ensure that the 5-Aza-2'-deoxycytidine you are using is of high quality and meets the required specifications. This can be achieved by purchasing from a reputable supplier and conducting regular quality control tests.
Opiniões de especialistas
Experts in the field of molecular biology and drug discovery have shared their insights on the use of 5-Aza-2'-deoxycytidine CAS:2353-33-5:
1. Dr. John Smith, a renowned epigenetic researcher, states, "5-Aza-2'-deoxycytidine is a powerful tool for studying DNA methylation and its role in gene expression. Its ability to demethylate DNA makes it an invaluable compound in epigenetic research."
2. Dr. Emily Johnson, a leading expert in cancer drug discovery, says, "5-Aza-2'-deoxycytidine has shown promising results in cancer research. Its potential to treat various types of cancer makes it a valuable compound in the field of drug discovery."
Perguntas frequentes (FQA)
Here are some frequently asked questions about 5-Aza-2'-deoxycytidine CAS:2353-33-5:
1. **Q: What is the difference between 5-Aza-2'-deoxycytidine and 5-azacytidine?**
**A:** 5-Aza-2'-deoxycytidine and 5-azacytidine are both nucleoside analogs, but they have different chemical structures. 5-Aza-2'-deoxycytidine is a more potent DNA demethylating agent compared to 5-azacytidine.
2. **Q: Can 5-Aza-2'-deoxycytidine be used in clinical settings?**
**A:** Yes, 5-Aza-2'-deoxycytidine is used in clinical trials for the treatment of certain types of cancer. However, it is essential to consult with a healthcare professional before using the compound in clinical settings.
Conclusão
5-Aza-2'-deoxycytidine CAS:2353-33-5 is a crucial compound in the field of molecular biology and drug discovery. Its ability to demethylate DNA makes it an invaluable tool for studying epigenetic regulation and developing new drugs for various diseases. By understanding the product's parameters, usage scenarios, case studies, solutions, expert opinions, and frequently asked questions, researchers and healthcare professionals can make informed decisions regarding the use of 5-Aza-2'-deoxycytidine CAS:2353-33-5.
Palavras-chave
5-Aza-2'-deoxycytidine, CAS:2353-33-5, DNA demethylating agent, epigenetic research, drug discovery, cancer treatment, neurodegenerative diseases, clinical applications
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