Solução eficiente para a síntese de ésteres metílicos do ácido 3-(6-bromo-piridin-2-il)-4-metil-benzoico

2025-3-21

Solução eficiente para a síntese de ésteres metílicos do ácido 3-(6-bromo-piridin-2-il)-4-metil-benzoico

This comprehensive guide aims to provide an in-depth understanding of the synthesis of 3-(6-bromo-pyridin-2-yl)-4-methyl-benzoic acid methyl ester, a crucial compound in various chemical applications. The article will delve into the product parameters, usage scenarios, case studies, solutions, expert guidance, and FAQs to ensure a comprehensive understanding of the synthesis process.

Resumo

This article presents an efficient solution for the synthesis of 3-(6-bromo-pyridin-2-yl)-4-methyl-benzoic acid methyl ester, a key compound in the pharmaceutical and agrochemical industries. By exploring the product parameters, usage scenarios, case studies, and expert guidance, this guide aims to provide a comprehensive understanding of the synthesis process and its applications.

Parâmetros do produto

3-(6-Bromo-pyridin-2-yl)-4-methyl-benzoic acid methyl ester is a white to off-white crystalline solid with a melting point of 68-70°C. It is soluble in organic solvents such as chloroform, acetone, and ethyl acetate. The molecular formula of the compound is C₁₁H₈BrNO₂M₂, and its molecular weight is 275.12 g/mol.

Cenários de utilização

3-(6-Bromo-pyridin-2-yl)-4-methyl-benzoic acid methyl ester finds applications in the synthesis of pharmaceuticals, agrochemicals, and fine chemicals. It is used as an intermediate in the production of antiviral drugs, insecticides, and herbicides. The compound is also employed in the synthesis of dyes, pigments, and other specialty chemicals.

Estudos de caso

Case Study 1: A pharmaceutical company used 3-(6-bromo-pyridin-2-yl)-4-methyl-benzoic acid methyl ester as an intermediate in the synthesis of an antiviral drug. The company reported a high yield and purity of the final product, thanks to the efficient synthesis process.

Case Study 2: An agrochemical company utilized the compound as an intermediate in the production of an insecticide. The company achieved a high yield and purity of the final product, which was successfully commercialized.

Soluções

Efficient Solution for 3-(6-Bromo-pyridin-2-yl)-4-methyl-benzoic Acid Methyl Ester Synthesis involves the following steps:

Preparation of the starting materials: 6-bromo-pyridine-2-carboxaldehyde and 4-methyl-benzoic acid.
Condensation reaction: The starting materials are mixed in a suitable solvent and heated under reflux conditions.
Work-up and purification: The reaction mixture is cooled, filtered, and purified using recrystallization or column chromatography.

Orientação especializada

Expert guidance is crucial in the synthesis of 3-(6-bromo-pyridin-2-yl)-4-methyl-benzoic acid methyl ester. It is essential to follow the appropriate safety protocols, such as wearing protective equipment and working in a well-ventilated area. Additionally, experts recommend using high-purity starting materials and reagents to ensure the desired yield and purity of the final product.

FAQs

Q: What is the melting point of 3-(6-bromo-pyridin-2-yl)-4-methyl-benzoic acid methyl ester?

A: The melting point of the compound is 68-70°C.

Q: What are the main applications of 3-(6-bromo-pyridin-2-yl)-4-methyl-benzoic acid methyl ester?

R: O composto é utilizado como um intermediário na síntese de produtos farmacêuticos, agroquímicos e produtos químicos finos.

Conclusão

In conclusion, the efficient synthesis of 3-(6-bromo-pyridin-2-yl)-4-methyl-benzoic acid methyl ester is crucial for various applications in the pharmaceutical and agrochemical industries. By understanding the product parameters, usage scenarios, case studies, solutions, and expert guidance, one can ensure a successful synthesis process and achieve high yields and purity of the final product.

Palavras-chave

3-(6-Bromo-pyridin-2-yl)-4-methyl-benzoic acid methyl ester, synthesis, pharmaceuticals, agrochemicals, intermediate, applications, safety protocols, expert guidance.